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Targeting Gαi/s Proteins with Peptidyl Nucleotide Exchange Modulators.
ACS Chem Biol. 2022 Feb 18;17(2):463-473. doi: 10.1021/acschembio.1c00929. Epub 2022 Jan 18.
ACS Chem Biol. 2022.
PMID: 35042325
Free PMC article.
Strategies towards Targeting Gαi/s Proteins: Scanning of Protein-Protein Interaction Sites To Overcome Inaccessibility.
Nubbemeyer B, Pepanian A, Paul George AA, Imhof D.
Nubbemeyer B, et al. Among authors: pepanian a.
ChemMedChem. 2021 Jun 7;16(11):1696-1715. doi: 10.1002/cmdc.202100039. Epub 2021 Mar 22.
ChemMedChem. 2021.
PMID: 33615736
Free PMC article.
Review.
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Fluorescence Anisotropy Assay with Guanine Nucleotides Provides Access to Functional Analysis of Gαi1 Proteins.
Pepanian A, Sommerfeld P, Kasprzyk R, Kühl T, Binbay FA, Hauser C, Löser R, Wodtke R, Bednarczyk M, Chrominski M, Kowalska J, Jemielity J, Imhof D, Pietsch M.
Pepanian A, et al.
Anal Chem. 2022 Oct 18;94(41):14410-14418. doi: 10.1021/acs.analchem.2c03176. Epub 2022 Oct 7.
Anal Chem. 2022.
PMID: 36206384
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Bicyclic Peptide Library Screening for the Identification of Gαi Protein Modulators.
Pepanian A, Binbay FA, Roy S, Nubbemeyer B, Koley A, Rhodes CA, Ammer H, Pei D, Ghosh P, Imhof D.
Pepanian A, et al.
J Med Chem. 2023 Sep 14;66(17):12396-12406. doi: 10.1021/acs.jmedchem.3c00873. Epub 2023 Aug 16.
J Med Chem. 2023.
PMID: 37587416
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In-depth analysis of Gαs protein activity by probing different fluorescently labeled guanine nucleotides.
Pepanian A, Sommerfeld P, Binbay FA, Fischer D, Pietsch M, Imhof D.
Pepanian A, et al.
Biol Chem. 2024 Feb 2;405(5):297-309. doi: 10.1515/hsz-2023-0321. Print 2024 May 27.
Biol Chem. 2024.
PMID: 38353111
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Design, synthesis, and analysis of macrobicyclic peptides for targeting the Gαi protein.
Pepanian A, Binbay FA, Pei D, Imhof D.
Pepanian A, et al.
J Pept Sci. 2024 Jun;30(6):e3565. doi: 10.1002/psc.3565. Epub 2024 Jan 17.
J Pept Sci. 2024.
PMID: 38232955
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