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The microglial NLRP3 inflammasome is involved in human SARS-CoV-2 cerebral pathogenicity: A report of three post-mortem cases.
Cama VF, Marín-Prida J, Acosta-Rivero N, Acosta EF, Díaz LO, Casadesús AV, Fernández-Marrero B, Gilva-Rodríguez N, Cremata-García D, Cervantes-Llanos M, Piniella-Matamoros B, Sánchez D, Del Rosario-Cruz L, Borrajero I, Díaz A, González Y, Pentón-Arias E, Montero-González T, Guillen-Nieto G, Pentón-Rol G. Cama VF, et al. Among authors: penton arias e. J Neuroimmunol. 2021 Dec 15;361:577728. doi: 10.1016/j.jneuroim.2021.577728. Epub 2021 Sep 29. J Neuroimmunol. 2021. PMID: 34619427 Free PMC article.
C-Phycocyanin ameliorates experimental autoimmune encephalomyelitis and induces regulatory T cells.
Pentón-Rol G, Martínez-Sánchez G, Cervantes-Llanos M, Lagumersindez-Denis N, Acosta-Medina EF, Falcón-Cama V, Alonso-Ramírez R, Valenzuela-Silva C, Rodríguez-Jiménez E, Llópiz-Arzuaga A, Marín-Prida J, López-Saura PA, Guillén-Nieto GE, Pentón-Arias E. Pentón-Rol G, et al. Int Immunopharmacol. 2011 Jan;11(1):29-38. doi: 10.1016/j.intimp.2010.10.001. Epub 2010 Oct 23. Int Immunopharmacol. 2011. PMID: 20971186
C-Phycocyanin is neuroprotective against global cerebral ischemia/reperfusion injury in gerbils.
Pentón-Rol G, Marín-Prida J, Pardo-Andreu G, Martínez-Sánchez G, Acosta-Medina EF, Valdivia-Acosta A, Lagumersindez-Denis N, Rodríguez-Jiménez E, Llópiz-Arzuaga A, López-Saura PA, Guillén-Nieto G, Pentón-Arias E. Pentón-Rol G, et al. Brain Res Bull. 2011 Aug 10;86(1-2):42-52. doi: 10.1016/j.brainresbull.2011.05.016. Epub 2011 Jun 6. Brain Res Bull. 2011. PMID: 21669260
C-Phycocyanin protects SH-SY5Y cells from oxidative injury, rat retina from transient ischemia and rat brain mitochondria from Ca2+/phosphate-induced impairment.
Marín-Prida J, Pentón-Rol G, Rodrigues FP, Alberici LC, Stringhetta K, Leopoldino AM, Naal Z, Polizello AC, Llópiz-Arzuaga A, Rosa MN, Liberato JL, Santos WF, Uyemura SA, Pentón-Arias E, Curti C, Pardo-Andreu GL. Marín-Prida J, et al. Brain Res Bull. 2012 Dec 1;89(5-6):159-67. doi: 10.1016/j.brainresbull.2012.08.011. Epub 2012 Sep 7. Brain Res Bull. 2012. PMID: 22982368 Free article.
Phycocyanobilin promotes PC12 cell survival and modulates immune and inflammatory genes and oxidative stress markers in acute cerebral hypoperfusion in rats.
Marín-Prida J, Pavón-Fuentes N, Llópiz-Arzuaga A, Fernández-Massó JR, Delgado-Roche L, Mendoza-Marí Y, Santana SP, Cruz-Ramírez A, Valenzuela-Silva C, Nazábal-Gálvez M, Cintado-Benítez A, Pardo-Andreu GL, Polentarutti N, Riva F, Pentón-Arias E, Pentón-Rol G. Marín-Prida J, et al. Toxicol Appl Pharmacol. 2013 Oct 1;272(1):49-60. doi: 10.1016/j.taap.2013.05.021. Epub 2013 Jun 2. Toxicol Appl Pharmacol. 2013. PMID: 23732081
Comparative Neuroregenerative Effects of C-Phycocyanin and IFN-Beta in a Model of Multiple Sclerosis in Mice.
Pentón-Rol G, Lagumersindez-Denis N, Muzio L, Bergami A, Furlan R, Fernández-Massó JR, Nazabal-Galvez M, Llópiz-Arzuaga A, Herrera-Rolo T, Veliz-Rodriguez T, Polentarutti N, Marín-Prida J, Raíces-Cruz I, Valenzuela-Silva C, Teixeira MM, Pentón-Arias E. Pentón-Rol G, et al. Among authors: penton arias e. J Neuroimmune Pharmacol. 2016 Mar;11(1):153-67. doi: 10.1007/s11481-015-9642-9. Epub 2015 Nov 10. J Neuroimmune Pharmacol. 2016. PMID: 26556034
Beneficial effects of oral administration of C-Phycocyanin and Phycocyanobilin in rodent models of experimental autoimmune encephalomyelitis.
Cervantes-Llanos M, Lagumersindez-Denis N, Marín-Prida J, Pavón-Fuentes N, Falcon-Cama V, Piniella-Matamoros B, Camacho-Rodríguez H, Fernández-Massó JR, Valenzuela-Silva C, Raíces-Cruz I, Pentón-Arias E, Teixeira MM, Pentón-Rol G. Cervantes-Llanos M, et al. Among authors: penton arias e. Life Sci. 2018 Feb 1;194:130-138. doi: 10.1016/j.lfs.2017.12.032. Epub 2017 Dec 27. Life Sci. 2018. PMID: 29287781
Phycocyanobilin reduces brain injury after endothelin-1- induced focal cerebral ischaemia.
Pavón-Fuentes N, Marín-Prida J, Llópiz-Arzuaga A, Falcón-Cama V, Campos-Mojena R, Cervantes-Llanos M, Piniella-Matamoros B, Pentón-Arias E, Pentón-Rol G. Pavón-Fuentes N, et al. Among authors: penton arias e. Clin Exp Pharmacol Physiol. 2020 Mar;47(3):383-392. doi: 10.1111/1440-1681.13214. Epub 2019 Dec 6. Clin Exp Pharmacol Physiol. 2020. PMID: 31732975
CIGB-258, a peptide derived from human heat-shock protein 60, decreases hyperinflammation in COVID-19 patients.
Hernandez-Cedeño M, Venegas-Rodriguez R, Peña-Ruiz R, Bequet-Romero M, Santana-Sanchez R, Penton-Arias E, Martinez-Donato G, Guillén-Nieto G, Dominguez-Horta MDC. Hernandez-Cedeño M, et al. Among authors: penton arias e. Cell Stress Chaperones. 2021 May;26(3):515-525. doi: 10.1007/s12192-021-01197-2. Epub 2021 Feb 24. Cell Stress Chaperones. 2021. PMID: 33629254 Free PMC article. Clinical Trial.
Anti-inflammatory mechanisms and pharmacological actions of phycocyanobilin in a mouse model of experimental autoimmune encephalomyelitis: A therapeutic promise for multiple sclerosis.
Marín-Prida J, Pavón-Fuentes N, Lagumersindez-Denis N, Camacho-Rodríguez H, García-Soca AM, Sarduy-Chávez RC, Vieira ÉLM, Carvalho-Tavares J, Falcón-Cama V, Fernández-Massó JR, Hernández-González I, Martínez-Donato G, Guillén-Nieto G, Pentón-Arias E, Teixeira MM, Pentón-Rol G. Marín-Prida J, et al. Among authors: penton arias e. Front Immunol. 2022 Nov 3;13:1036200. doi: 10.3389/fimmu.2022.1036200. eCollection 2022. Front Immunol. 2022. PMID: 36405721 Free PMC article.
14 results