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Page 1
Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state.
Cerezo-Wallis D, Contreras-Alcalde M, Troulé K, Catena X, Mucientes C, Calvo TG, Cañón E, Tejedo C, Pennacchi PC, Hogan S, Kölblinger P, Tejero H, Chen AX, Ibarz N, Graña-Castro O, Martinez L, Muñoz J, Ortiz-Romero P, Rodriguez-Peralto JL, Gómez-López G, Al-Shahrour F, Rabadán R, Levesque MP, Olmeda D, Soengas MS. Cerezo-Wallis D, et al. Among authors: pennacchi pc. Nat Med. 2020 Dec;26(12):1865-1877. doi: 10.1038/s41591-020-1073-3. Epub 2020 Oct 19. Nat Med. 2020. PMID: 33077955
Whole-body imaging of lymphovascular niches identifies pre-metastatic roles of midkine.
Olmeda D, Cerezo-Wallis D, Riveiro-Falkenbach E, Pennacchi PC, Contreras-Alcalde M, Ibarz N, Cifdaloz M, Catena X, Calvo TG, Cañón E, Alonso-Curbelo D, Suarez J, Osterloh L, Graña O, Mulero F, Megías D, Cañamero M, Martínez-Torrecuadrada JL, Mondal C, Di Martino J, Lora D, Martinez-Corral I, Bravo-Cordero JJ, Muñoz J, Puig S, Ortiz-Romero P, Rodriguez-Peralto JL, Ortega S, Soengas MS. Olmeda D, et al. Among authors: pennacchi pc. Nature. 2017 Jun 28;546(7660):676-680. doi: 10.1038/nature22977. Nature. 2017. PMID: 28658220 Free PMC article.
Vemurafenib resistance increases melanoma invasiveness and modulates the tumor microenvironment by MMP-2 upregulation.
Sandri S, Faião-Flores F, Tiago M, Pennacchi PC, Massaro RR, Alves-Fernandes DK, Berardinelli GN, Evangelista AF, de Lima Vazquez V, Reis RM, Maria-Engler SS. Sandri S, et al. Among authors: pennacchi pc. Pharmacol Res. 2016 Sep;111:523-533. doi: 10.1016/j.phrs.2016.07.017. Epub 2016 Jul 18. Pharmacol Res. 2016. PMID: 27436149 Free article.
Targeting the hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cells.
Faião-Flores F, Alves-Fernandes DK, Pennacchi PC, Sandri S, Vicente AL, Scapulatempo-Neto C, Vazquez VL, Reis RM, Chauhan J, Goding CR, Smalley KS, Maria-Engler SS. Faião-Flores F, et al. Among authors: pennacchi pc. Oncogene. 2017 Mar 30;36(13):1849-1861. doi: 10.1038/onc.2016.348. Epub 2016 Oct 17. Oncogene. 2017. PMID: 27748762 Free PMC article.
Fibroblasts protect melanoma cells from the cytotoxic effects of doxorubicin.
Tiago M, de Oliveira EM, Brohem CA, Pennacchi PC, Paes RD, Haga RB, Campa A, de Moraes Barros SB, Smalley KS, Maria-Engler SS. Tiago M, et al. Among authors: pennacchi pc. Tissue Eng Part A. 2014 Sep;20(17-18):2412-21. doi: 10.1089/ten.TEA.2013.0473. Epub 2014 Mar 25. Tissue Eng Part A. 2014. PMID: 24548268 Free PMC article.
MMP-9/RECK Imbalance: A Mechanism Associated with High-Grade Cervical Lesions and Genital Infection by Human Papillomavirus and Chlamydia trachomatis.
Discacciati MG, Gimenes F, Pennacchi PC, Faião-Flores F, Zeferino LC, Derchain SM, Teixeira JC, Costa MC, Zonta M, Termini L, Boccardo E, Longatto-Filho A, Consolaro ME, Villa LL, Maria-Engler SS. Discacciati MG, et al. Among authors: pennacchi pc. Cancer Epidemiol Biomarkers Prev. 2015 Oct;24(10):1539-47. doi: 10.1158/1055-9965.EPI-15-0420. Epub 2015 Aug 10. Cancer Epidemiol Biomarkers Prev. 2015. PMID: 26261088
LINE-1 hypomethylation and mutational status in cutaneous melanomas.
Pramio DT, Pennacchi PC, Maria-Engler SS, Campos AH, Duprat JP, Carraro DM, Krepischi AC. Pramio DT, et al. Among authors: pennacchi pc. J Investig Med. 2016 Apr;64(4):899-904. doi: 10.1136/jim-2016-000066. Epub 2016 Mar 10. J Investig Med. 2016. PMID: 26965315
18 results