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Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition.
Waters AM, Khatib TO, Papke B, Goodwin CM, Hobbs GA, Diehl JN, Yang R, Edwards AC, Walsh KH, Sulahian R, McFarland JM, Kapner KS, Gilbert TSK, Stalnecker CA, Javaid S, Barkovskaya A, Grover KR, Hibshman PS, Blake DR, Schaefer A, Nowak KM, Klomp JE, Hayes TK, Kassner M, Tang N, Tanaseichuk O, Chen K, Zhou Y, Kalkat M, Herring LE, Graves LM, Penn LZ, Yin HH, Aguirre AJ, Hahn WC, Cox AD, Der CJ. Waters AM, et al. Among authors: penn lz. Cell Rep. 2021 Jun 29;35(13):109291. doi: 10.1016/j.celrep.2021.109291. Cell Rep. 2021. PMID: 34192548 Free PMC article.
More than MAX: Discovering the Myc interactome.
Kalkat M, Wasylishen AR, Kim SS, Penn L. Kalkat M, et al. Cell Cycle. 2011 Feb 1;10(3):374-5. doi: 10.4161/cc.10.3.14645. Epub 2011 Feb 1. Cell Cycle. 2011. PMID: 21270515 No abstract available.
MYC activity is negatively regulated by a C-terminal lysine cluster.
Wasylishen AR, Kalkat M, Kim SS, Pandyra A, Chan PK, Oliveri S, Sedivy E, Konforte D, Bros C, Raught B, Penn LZ. Wasylishen AR, et al. Among authors: penn lz. Oncogene. 2014 Feb 20;33(8):1066-72. doi: 10.1038/onc.2013.36. Epub 2013 Feb 25. Oncogene. 2014. PMID: 23435422
MYC phosphorylation at novel regulatory regions suppresses transforming activity.
Wasylishen AR, Chan-Seng-Yue M, Bros C, Dingar D, Tu WB, Kalkat M, Chan PK, Mullen PJ, Huang L, Meyer N, Raught B, Boutros PC, Penn LZ. Wasylishen AR, et al. Among authors: penn lz. Cancer Res. 2013 Nov 1;73(21):6504-15. doi: 10.1158/0008-5472.CAN-12-4063. Epub 2013 Sep 12. Cancer Res. 2013. PMID: 24030976
Identification of c-MYC SUMOylation by mass spectrometry.
Kalkat M, Chan PK, Wasylishen AR, Srikumar T, Kim SS, Ponzielli R, Bazett-Jones DP, Raught B, Penn LZ. Kalkat M, et al. Among authors: penn lz. PLoS One. 2014 Dec 18;9(12):e115337. doi: 10.1371/journal.pone.0115337. eCollection 2014. PLoS One. 2014. PMID: 25522242 Free PMC article.
Modelling the MYC-driven normal-to-tumour switch in breast cancer.
Lourenco C, Kalkat M, Houlahan KE, De Melo J, Longo J, Done SJ, Boutros PC, Penn LZ. Lourenco C, et al. Among authors: penn lz. Dis Model Mech. 2019 Jul 26;12(7):dmm038083. doi: 10.1242/dmm.038083. Dis Model Mech. 2019. PMID: 31350286 Free PMC article.
129 results