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Calcineurin regulates bone formation by the osteoblast.
Sun L, Blair HC, Peng Y, Zaidi N, Adebanjo OA, Wu XB, Wu XY, Iqbal J, Epstein S, Abe E, Moonga BS, Zaidi M. Sun L, et al. Among authors: peng y. Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):17130-5. doi: 10.1073/pnas.0508480102. Epub 2005 Nov 14. Proc Natl Acad Sci U S A. 2005. PMID: 16286645 Free PMC article.
Further evidence for direct pro-resorptive actions of FSH.
Sun L, Zhang Z, Zhu LL, Peng Y, Liu X, Li J, Agrawal M, Robinson LJ, Iqbal J, Blair HC, Zaidi M. Sun L, et al. Among authors: peng y. Biochem Biophys Res Commun. 2010 Mar 26;394(1):6-11. doi: 10.1016/j.bbrc.2010.02.113. Epub 2010 Feb 19. Biochem Biophys Res Commun. 2010. PMID: 20171951 Free PMC article.
FSH directly regulates bone mass.
Sun L, Peng Y, Sharrow AC, Iqbal J, Zhang Z, Papachristou DJ, Zaidi S, Zhu LL, Yaroslavskiy BB, Zhou H, Zallone A, Sairam MR, Kumar TR, Bo W, Braun J, Cardoso-Landa L, Schaffler MB, Moonga BS, Blair HC, Zaidi M. Sun L, et al. Among authors: peng y. Cell. 2006 Apr 21;125(2):247-60. doi: 10.1016/j.cell.2006.01.051. Cell. 2006. PMID: 16630814 Free article.
Evidence that calcineurin is required for the genesis of bone-resorbing osteoclasts.
Sun L, Peng Y, Zaidi N, Zhu LL, Iqbal J, Yamoah K, Wang X, Liu P, Abe E, Moonga BS, Epstein S, Zaidi M. Sun L, et al. Among authors: peng y. Am J Physiol Renal Physiol. 2007 Jan;292(1):F285-91. doi: 10.1152/ajprenal.00415.2005. Epub 2006 Sep 12. Am J Physiol Renal Physiol. 2007. PMID: 16968888 Free article.
Oxytocin deficiency impairs maternal skeletal remodeling.
Liu X, Shimono K, Zhu LL, Li J, Peng Y, Imam A, Iqbal J, Moonga S, Colaianni G, Su C, Lu Z, Iwamoto M, Pacifici M, Zallone A, Sun L, Zaidi M. Liu X, et al. Among authors: peng y. Biochem Biophys Res Commun. 2009 Oct 9;388(1):161-6. doi: 10.1016/j.bbrc.2009.07.148. Epub 2009 Aug 3. Biochem Biophys Res Commun. 2009. PMID: 19653998
ACTH protects against glucocorticoid-induced osteonecrosis of bone.
Zaidi M, Sun L, Robinson LJ, Tourkova IL, Liu L, Wang Y, Zhu LL, Liu X, Li J, Peng Y, Yang G, Shi X, Levine A, Iqbal J, Yaroslavskiy BB, Isales C, Blair HC. Zaidi M, et al. Among authors: peng y. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8782-7. doi: 10.1073/pnas.0912176107. Epub 2010 Apr 26. Proc Natl Acad Sci U S A. 2010. PMID: 20421485 Free PMC article.
TNFalpha mediates the skeletal effects of thyroid-stimulating hormone.
Hase H, Ando T, Eldeiry L, Brebene A, Peng Y, Liu L, Amano H, Davies TF, Sun L, Zaidi M, Abe E. Hase H, et al. Among authors: peng y. Proc Natl Acad Sci U S A. 2006 Aug 22;103(34):12849-54. doi: 10.1073/pnas.0600427103. Epub 2006 Aug 14. Proc Natl Acad Sci U S A. 2006. PMID: 16908863 Free PMC article.
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