Peng T - Search Results

1

Inhibitors of phosphodiesterase as cancer therapeutics.

Peng T, Gong J, Jin Y, Zhou Y, Tong R, Wei X, Bai L, Shi J. Peng T, et al. Eur J Med Chem. 2018 Apr 25;150:742-756. doi: 10.1016/j.ejmech.2018.03.046. Epub 2018 Mar 16. Eur J Med Chem. 2018. PMID: 29574203 Review.

2

Advances in the Development of Phosphodiesterase-4 Inhibitors.

Peng T, Qi B, He J, Ke H, Shi J. Peng T, et al. J Med Chem. 2020 Oct 8;63(19):10594-10617. doi: 10.1021/acs.jmedchem.9b02170. Epub 2020 Jun 10. J Med Chem. 2020. PMID: 32255344 Review.

3

Discovery of N-(3-bromo-1H-indol-5-yl)-quinazolin-4-amine as an effective molecular skeleton to develop reversible/irreversible pan-HER inhibitors.

Tang Q, Peng T, Hu J, Zhang T, Chen P, Chen D, Wang Y, Chen L, Tong L, Chen Y, Xie H, Liang G. Tang Q, et al. Among authors: peng t. Eur J Med Chem. 2022 Apr 5;233:114249. doi: 10.1016/j.ejmech.2022.114249. Epub 2022 Mar 2. Eur J Med Chem. 2022. PMID: 35259690

4

Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma.

Zhou Z, Li Y, Ma X, Cao B, Peng T, Sheng Y, Peng H, Li R, Cao Y, Xi R, Li F, Wang M, Sun H, Zhang G, Zhang H, Hu K, Xiao W, Wang F. Zhou Z, et al. Among authors: peng t, peng h. J Med Chem. 2021 Jun 10;64(11):7404-7421. doi: 10.1021/acs.jmedchem.1c00018. Epub 2021 May 26. J Med Chem. 2021. PMID: 34038111

5

Naphthalimides exhibit in vitro antiproliferative and antiangiogenic activities by inhibiting both topoisomerase II (topo II) and receptor tyrosine kinases (RTKs).

Wang X, Chen Z, Tong L, Tan S, Zhou W, Peng T, Han K, Ding J, Xie H, Xu Y. Wang X, et al. Among authors: peng t. Eur J Med Chem. 2013 Jul;65:477-86. doi: 10.1016/j.ejmech.2013.05.002. Epub 2013 May 14. Eur J Med Chem. 2013. PMID: 23770449

6

Discovery and SAR of thiazolidine-2,4-dione analogues as insulin-like growth factor-1 receptor (IGF-1R) inhibitors via hierarchical virtual screening.

Liu X, Xie H, Luo C, Tong L, Wang Y, Peng T, Ding J, Jiang H, Li H. Liu X, et al. Among authors: peng t. J Med Chem. 2010 Mar 25;53(6):2661-5. doi: 10.1021/jm901798e. J Med Chem. 2010. PMID: 20178321 Free article.

7

Topoisomerase II inhibitors from the roots of Stellera chamaejasme L.

Liu LP, Han K, Chen W, Zhang YY, Tong LJ, Peng T, Xie H, Ding J, Wang HB. Liu LP, et al. Among authors: peng t. Bioorg Med Chem. 2014 Aug 1;22(15):4198-203. doi: 10.1016/j.bmc.2014.05.042. Epub 2014 May 29. Bioorg Med Chem. 2014. PMID: 24931277

8

Design, synthesis and biological evaluation of novel 4-anilinoquinazolines with C-6 urea-linked side chains as inhibitors of the epidermal growth factor receptor.

Zhang X, Peng T, Ji X, Li J, Tong L, Li Z, Yang W, Xu Y, Li M, Ding J, Jiang H, Xie H, Liu H. Zhang X, et al. Among authors: peng t. Bioorg Med Chem. 2013 Dec 15;21(24):7988-98. doi: 10.1016/j.bmc.2013.09.049. Epub 2013 Oct 2. Bioorg Med Chem. 2013. PMID: 24183742

9

Design, synthesis and biological evaluation of novel 6-alkenylamides substituted of 4-anilinothieno[2,3-d]pyrimidines as irreversible epidermal growth factor receptor inhibitors.

Ji X, Peng T, Zhang X, Li J, Yang W, Tong L, Qu R, Jiang H, Ding J, Xie H, Liu H. Ji X, et al. Among authors: peng t. Bioorg Med Chem. 2014 Apr 1;22(7):2366-78. doi: 10.1016/j.bmc.2014.01.035. Epub 2014 Jan 31. Bioorg Med Chem. 2014. PMID: 24565969

10

Discovery of a Novel Small-Molecule Inhibitor Disrupting TRBP-Dicer Interaction against Hepatocellular Carcinoma via the Modulation of microRNA Biogenesis.

Peng T, He Y, Wang T, Yu J, Ma X, Zhou Z, Sheng Y, Li L, Peng H, Li S, Zou J, Yuan Y, Zhao Y, Shi H, Li F, Liu W, Hu K, Lu X, Zhang G, Wang F. Peng T, et al. Among authors: peng h. J Med Chem. 2022 Aug 25;65(16):11010-11033. doi: 10.1021/acs.jmedchem.2c00189. Epub 2022 Jun 13. J Med Chem. 2022. PMID: 35695407

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