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PAAN/MIF nuclease inhibition prevents neurodegeneration in Parkinson's disease.
Park H, Kam TI, Peng H, Chou SC, Mehrabani-Tabari AA, Song JJ, Yin X, Karuppagounder SS, Umanah GK, Rao AVS, Choi Y, Aggarwal A, Chang S, Kim H, Byun J, Liu JO, Dawson TM, Dawson VL. Park H, et al. Among authors: peng h. Cell. 2022 May 26;185(11):1943-1959.e21. doi: 10.1016/j.cell.2022.04.020. Epub 2022 May 10. Cell. 2022. PMID: 35545089 Free PMC article.
Discovery of a Potent GLUT Inhibitor from a Library of Rapafucins by Using 3D Microarrays.
Guo Z, Cheng Z, Wang J, Liu W, Peng H, Wang Y, Rao AVS, Li RJ, Ying X, Korangath P, Liberti MV, Li Y, Xie Y, Hong SY, Schiene-Fischer C, Fischer G, Locasale JW, Sukumar S, Zhu H, Liu JO. Guo Z, et al. Among authors: peng h. Angew Chem Int Ed Engl. 2019 Nov 25;58(48):17158-17162. doi: 10.1002/anie.201905578. Epub 2019 Oct 31. Angew Chem Int Ed Engl. 2019. PMID: 31591797 Free PMC article.
Rapamycin-inspired macrocycles with new target specificity.
Guo Z, Hong SY, Wang J, Rehan S, Liu W, Peng H, Das M, Li W, Bhat S, Peiffer B, Ullman BR, Tse CM, Tarmakova Z, Schiene-Fischer C, Fischer G, Coe I, Paavilainen VO, Sun Z, Liu JO. Guo Z, et al. Among authors: peng h. Nat Chem. 2019 Mar;11(3):254-263. doi: 10.1038/s41557-018-0187-4. Epub 2018 Dec 10. Nat Chem. 2019. PMID: 30532015 Free PMC article.
BET family protein degraders poised to join the senolytic arsenal.
Guo Z, Peng H, Xie Y. Guo Z, et al. Among authors: peng h. Signal Transduct Target Ther. 2020 Jun 10;5(1):88. doi: 10.1038/s41392-020-0202-2. Signal Transduct Target Ther. 2020. PMID: 32528000 Free PMC article. No abstract available.
9,534 results