Peng C - Search Results

1

5-Substituted-N-pyridazinylbenzamides as potent and selective LRRK2 inhibitors: Improved brain unbound fraction enables efficacy.

Ding X, Stasi LP, Dai X, Long K, Peng C, Zhao B, Wang H, Sun C, Hu H, Wan Z, Jandu KS, Philps OJ, Chen Y, Wang L, Liu Q, Edge C, Li Y, Dong K, Guan X, Tattersall FD, Reith AD, Ren F. Ding X, et al. Among authors: peng c. Bioorg Med Chem Lett. 2019 Jan 15;29(2):212-215. doi: 10.1016/j.bmcl.2018.11.054. Epub 2018 Nov 28. Bioorg Med Chem Lett. 2019. PMID: 30522952

2

Discovery of 5-substituent-N-arylbenzamide derivatives as potent, selective and orally bioavailable LRRK2 inhibitors.

Ding X, Dai X, Long K, Peng C, Andreotti D, Bamborough P, Eatherton AJ, Edge C, Jandu KS, Nichols PL, Philps OJ, Stasi LP, Wan Z, Xiang JN, Dong K, Dossang P, Ho MH, Li Y, Mensah L, Guan X, Reith AD, Ren F. Ding X, et al. Among authors: peng c. Bioorg Med Chem Lett. 2017 Sep 1;27(17):4034-4038. doi: 10.1016/j.bmcl.2017.07.052. Epub 2017 Jul 21. Bioorg Med Chem Lett. 2017. PMID: 28774425

3

Inhibitor development of MTH1 via high-throughput screening with fragment based library and MTH1 substrate binding cavity.

Peng C, Li YH, Yu CW, Cheng ZH, Liu JR, Hsu JL, Hsin LW, Huang CT, Juan HF, Chern JW, Cheng YS. Peng C, et al. Bioorg Chem. 2021 May;110:104813. doi: 10.1016/j.bioorg.2021.104813. Epub 2021 Mar 10. Bioorg Chem. 2021. PMID: 33774493 Free article.

4

Small-molecule dual inhibitors targeting heat shock protein 90 for cancer targeted therapy.

Xie X, Zhang N, Li X, Huang H, Peng C, Huang W, Foster LJ, He G, Han B. Xie X, et al. Among authors: peng c. Bioorg Chem. 2023 Oct;139:106721. doi: 10.1016/j.bioorg.2023.106721. Epub 2023 Jul 8. Bioorg Chem. 2023. PMID: 37467620 Review.

5

Discovery of tetrahydrofuranyl spirooxindole-based SMYD3 inhibitors against gastric cancer via inducing lethal autophagy.

Zhu HP, Chai J, Qin R, Leng HJ, Wen X, Peng C, He G, Han B. Zhu HP, et al. Among authors: peng c. Eur J Med Chem. 2023 Jan 15;246:115009. doi: 10.1016/j.ejmech.2022.115009. Epub 2022 Dec 6. Eur J Med Chem. 2023. PMID: 36527933

6

Sulfite-Assisted Acetate Conversion from CO Electroreduction.

Ma J, Liu T, Hao S, Yan S, Xu Z, Yang S, Shen H, Jing Y, Peng C. Ma J, et al. Among authors: peng c. ChemSusChem. 2024 May 20:e202400683. doi: 10.1002/cssc.202400683. Online ahead of print. ChemSusChem. 2024. PMID: 38769898

7

A novel enzyme-linked immunosorbent assay tool to evaluate plasma soluble CD226 in primary Sjögren's syndrome.

Ding S, Zhao P, Song S, Yang Y, Peng C, Chang X, Liu C. Ding S, et al. Among authors: peng c. Anal Biochem. 2024 May 18:115573. doi: 10.1016/j.ab.2024.115573. Online ahead of print. Anal Biochem. 2024. PMID: 38768695

8

Phycosphere bacterial disturbance of Saccharina japonica caused by white rot disease relates to seawater nutrients.

Ma C, Peng C, Fu L, Ren C, Liu X, Liu Z, Qin S, Zhong Z. Ma C, et al. Among authors: peng c. Environ Sci Pollut Res Int. 2024 May 20. doi: 10.1007/s11356-024-33707-x. Online ahead of print. Environ Sci Pollut Res Int. 2024. PMID: 38767795

9

Purification of gamma-cyclodextrin via selective coordination with potassium ions to form metal-organic frameworks.

Baqing L, He X, Ni Q, Zhang H, Li T, Lin X, Guo T, Garba BM, Chen X, Zhang J, Peng C, Wang C, Wu L. Baqing L, et al. Among authors: peng c. Carbohydr Polym. 2024 Aug 15;338:122193. doi: 10.1016/j.carbpol.2024.122193. Epub 2024 Apr 22. Carbohydr Polym. 2024. PMID: 38763708

10

Mycobacterium tuberculosis suppresses host antimicrobial peptides by dehydrogenating L-alanine.

Peng C, Cheng Y, Ma M, Chen Q, Duan Y, Liu S, Cheng H, Yang H, Huang J, Bu W, Shi C, Wu X, Chen J, Zheng R, Liu Z, Ji Z, Wang J, Huang X, Wang P, Sha W, Ge B, Wang L. Peng C, et al. Nat Commun. 2024 May 17;15(1):4216. doi: 10.1038/s41467-024-48588-4. Nat Commun. 2024. PMID: 38760394 Free PMC article.

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