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Regulatory T cells promote myelin regeneration in the central nervous system.
Dombrowski Y, O'Hagan T, Dittmer M, Penalva R, Mayoral SR, Bankhead P, Fleville S, Eleftheriadis G, Zhao C, Naughton M, Hassan R, Moffat J, Falconer J, Boyd A, Hamilton P, Allen IV, Kissenpfennig A, Moynagh PN, Evergren E, Perbal B, Williams AC, Ingram RJ, Chan JR, Franklin RJM, Fitzgerald DC. Dombrowski Y, et al. Among authors: penalva r. Nat Neurosci. 2017 May;20(5):674-680. doi: 10.1038/nn.4528. Epub 2017 Mar 13. Nat Neurosci. 2017. PMID: 28288125 Free PMC article.
The microbiota regulates murine inflammatory responses to toxin-induced CNS demyelination but has minimal impact on remyelination.
McMurran CE, Guzman de la Fuente A, Penalva R, Ben Menachem-Zidon O, Dombrowski Y, Falconer J, Gonzalez GA, Zhao C, Krause FN, Young AMH, Griffin JL, Jones CA, Hollins C, Heimesaat MM, Fitzgerald DC, Franklin RJM. McMurran CE, et al. Among authors: penalva r. Proc Natl Acad Sci U S A. 2019 Dec 10;116(50):25311-25321. doi: 10.1073/pnas.1905787116. Epub 2019 Nov 18. Proc Natl Acad Sci U S A. 2019. PMID: 31740610 Free PMC article.
Dynamic CCN3 expression in the murine CNS does not confer essential roles in myelination or remyelination.
de la Vega Gallardo N, Penalva R, Dittmer M, Naughton M, Falconer J, Moffat J, de la Fuente AG, Hombrebueno JR, Lin Z, Perbal B, Ingram RJ, Evergren E, Fitzgerald DC. de la Vega Gallardo N, et al. Among authors: penalva r. Proc Natl Acad Sci U S A. 2020 Jul 28;117(30):18018-18028. doi: 10.1073/pnas.1922089117. Epub 2020 Jul 10. Proc Natl Acad Sci U S A. 2020. PMID: 32651278 Free PMC article.
Ageing impairs the regenerative capacity of regulatory T cells in mouse central nervous system remyelination.
de la Fuente AG, Dittmer M, Heesbeen EJ, de la Vega Gallardo N, White JA, Young A, McColgan T, Dashwood A, Mayne K, Cabeza-Fernández S, Falconer J, Rodriguez-Baena FJ, McMurran CE, Inayatullah M, Rawji KS, Franklin RJM, Dooley J, Liston A, Ingram RJ, Tiwari VK, Penalva R, Dombrowski Y, Fitzgerald DC. de la Fuente AG, et al. Among authors: penalva r. Nat Commun. 2024 Mar 11;15(1):1870. doi: 10.1038/s41467-024-45742-w. Nat Commun. 2024. PMID: 38467607 Free PMC article.
Regulatory T cells limit age-associated retinal inflammation and neurodegeneration.
Llorián-Salvador M, de Fuente AG, McMurran CE, Dashwood A, Dooley J, Liston A, Penalva R, Dombrowski Y, Stitt AW, Fitzgerald DC. Llorián-Salvador M, et al. Among authors: penalva r. Mol Neurodegener. 2024 Apr 5;19(1):32. doi: 10.1186/s13024-024-00724-w. Mol Neurodegener. 2024. PMID: 38581053 Free PMC article.
26 results