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The in vivo and in vitro roles of Trypanosoma cruzi Rad51 in the repair of DNA double strand breaks and oxidative lesions.
Gomes Passos Silva D, da Silva Santos S, Nardelli SC, Mendes IC, Freire ACG, Repolês BM, Resende BC, Costa-Silva HM, da Silva VS, Oliveira KA, Oliveira CFB, Vilela LFF, Nagem RAP, Franco GR, Macedo AM, Pena SDJ, Tahara EB, Sales Junior PA, Moreira DS, Teixeira SMR, McCulloch R, Virgilio S, Tosi LRO, Schenkman S, Andrade LO, Murta SMF, Machado CR. Gomes Passos Silva D, et al. Among authors: pena sdj. PLoS Negl Trop Dis. 2018 Nov 13;12(11):e0006875. doi: 10.1371/journal.pntd.0006875. eCollection 2018 Nov. PLoS Negl Trop Dis. 2018. PMID: 30422982 Free PMC article.
Characterization of the Trypanosoma cruzi Rad51 gene and its role in recombination events associated with the parasite resistance to ionizing radiation.
Regis-da-Silva CG, Freitas JM, Passos-Silva DG, Furtado C, Augusto-Pinto L, Pereira MT, DaRocha WD, Franco GR, Macedo AM, Hoffmann JS, Cazaux C, Pena SD, Teixeira SM, Machado CR. Regis-da-Silva CG, et al. Mol Biochem Parasitol. 2006 Oct;149(2):191-200. doi: 10.1016/j.molbiopara.2006.05.012. Epub 2006 Jun 21. Mol Biochem Parasitol. 2006. PMID: 16828179
DNA polymerase beta from Trypanosoma cruzi is involved in kinetoplast DNA replication and repair of oxidative lesions.
Schamber-Reis BL, Nardelli S, Régis-Silva CG, Campos PC, Cerqueira PG, Lima SA, Franco GR, Macedo AM, Pena SD, Cazaux C, Hoffmann JS, Motta MC, Schenkman S, Teixeira SM, Machado CR. Schamber-Reis BL, et al. Mol Biochem Parasitol. 2012 Jun;183(2):122-31. doi: 10.1016/j.molbiopara.2012.02.007. Epub 2012 Feb 24. Mol Biochem Parasitol. 2012. PMID: 22369885 Free article.
Functional characterization of 8-oxoguanine DNA glycosylase of Trypanosoma cruzi.
Furtado C, Kunrath-Lima M, Rajão MA, Mendes IC, de Moura MB, Campos PC, Macedo AM, Franco GR, Pena SD, Teixeira SM, Van Houten B, Machado CR. Furtado C, et al. PLoS One. 2012;7(8):e42484. doi: 10.1371/journal.pone.0042484. Epub 2012 Aug 2. PLoS One. 2012. PMID: 22876325 Free PMC article.
Unveiling benznidazole's mechanism of action through overexpression of DNA repair proteins in Trypanosoma cruzi.
Rajão MA, Furtado C, Alves CL, Passos-Silva DG, de Moura MB, Schamber-Reis BL, Kunrath-Lima M, Zuma AA, Vieira-da-Rocha JP, Garcia JB, Mendes IC, Pena SD, Macedo AM, Franco GR, de Souza-Pinto NC, de Medeiros MH, Cruz AK, Motta MC, Teixeira SM, Machado CR. Rajão MA, et al. Environ Mol Mutagen. 2014 May;55(4):309-21. doi: 10.1002/em.21839. Epub 2013 Dec 18. Environ Mol Mutagen. 2014. PMID: 24347026
Catalase expression impairs oxidative stress-mediated signalling in Trypanosoma cruzi.
Freire ACG, Alves CL, Goes GR, Resende BC, Moretti NS, Nunes VS, Aguiar PHN, Tahara EB, Franco GR, Macedo AM, Pena SDJ, Gadelha FR, Guarneri AA, Schenkman S, Vieira LQ, Machado CR. Freire ACG, et al. Among authors: pena sdj. Parasitology. 2017 Sep;144(11):1498-1510. doi: 10.1017/S0031182017001044. Epub 2017 Jun 27. Parasitology. 2017. PMID: 28653592
139 results