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Page 1
A rectal cancer organoid platform to study individual responses to chemoradiation.
Ganesh K, Wu C, O'Rourke KP, Szeglin BC, Zheng Y, Sauvé CG, Adileh M, Wasserman I, Marco MR, Kim AS, Shady M, Sanchez-Vega F, Karthaus WR, Won HH, Choi SH, Pelossof R, Barlas A, Ntiamoah P, Pappou E, Elghouayel A, Strong JS, Chen CT, Harris JW, Weiser MR, Nash GM, Guillem JG, Wei IH, Kolesnick RN, Veeraraghavan H, Ortiz EJ, Petkovska I, Cercek A, Manova-Todorova KO, Saltz LB, Lavery JA, DeMatteo RP, Massagué J, Paty PB, Yaeger R, Chen X, Patil S, Clevers H, Berger MF, Lowe SW, Shia J, Romesser PB, Dow LE, Garcia-Aguilar J, Sawyers CL, Smith JJ. Ganesh K, et al. Among authors: pelossof r. Nat Med. 2019 Oct;25(10):1607-1614. doi: 10.1038/s41591-019-0584-2. Epub 2019 Oct 7. Nat Med. 2019. PMID: 31591597 Free PMC article.
Genomic and transcriptomic determinants of response to neoadjuvant therapy in rectal cancer.
Chatila WK, Kim JK, Walch H, Marco MR, Chen CT, Wu F, Omer DM, Khalil DN, Ganesh K, Qu X, Luthra A, Choi SH, Ho YJ, Kundra R, Groves KI, Chow OS, Cercek A, Weiser MR, Widmar M, Wei IH, Pappou EP, Nash GM, Paty PB, Shi Q, Vakiani E, Duygu Selcuklu S, Donoghue MTA, Solit DB, Berger MF, Shia J, Pelossof R, Romesser PB, Yaeger R, Smith JJ, Schultz N, Sanchez-Vega F, Garcia-Aguilar J. Chatila WK, et al. Among authors: pelossof r. Nat Med. 2022 Aug;28(8):1646-1655. doi: 10.1038/s41591-022-01930-z. Epub 2022 Aug 15. Nat Med. 2022. PMID: 35970919 Free PMC article.
KRAS mutant rectal cancer cells interact with surrounding fibroblasts to deplete the extracellular matrix.
Kim JK, Marco MR, Choi SH, Qu X, Chen CT, Elkabets M, Fairchild L, Chow O, Barriga FM, Dow LE, O'Rourke K, Szeglin B, Yarilin D, Fujisawa S, Manova-Todorova K, Paty PB, Shia J, Leslie C, Smith JJ, Lowe S, Pelossof R, Sanchez-Vega F, Garcia-Aguilar J. Kim JK, et al. Among authors: pelossof r. Mol Oncol. 2021 Oct;15(10):2766-2781. doi: 10.1002/1878-0261.12960. Epub 2021 Jun 15. Mol Oncol. 2021. PMID: 33817986 Free PMC article.
KRAS Mutants Upregulate Integrin β4 to Promote Invasion and Metastasis in Colorectal Cancer.
Choi SH, Kim JK, Chen CT, Wu C, Marco MR, Barriga FM, O'Rourke K, Pelossof R, Qu X, Chang Q, de Stanchina E, Shia J, Smith JJ, Sanchez-Vega F, Garcia-Aguilar J. Choi SH, et al. Among authors: pelossof r. Mol Cancer Res. 2022 Aug 5;20(8):1305-1319. doi: 10.1158/1541-7786.MCR-21-0994. Mol Cancer Res. 2022. PMID: 35394541 Free PMC article.
KRAS and Combined KRAS/TP53 Mutations in Locally Advanced Rectal Cancer are Independently Associated with Decreased Response to Neoadjuvant Therapy.
Chow OS, Kuk D, Keskin M, Smith JJ, Camacho N, Pelossof R, Chen CT, Chen Z, Avila K, Weiser MR, Berger MF, Patil S, Bergsland E, Garcia-Aguilar J. Chow OS, et al. Among authors: pelossof r. Ann Surg Oncol. 2016 Aug;23(8):2548-55. doi: 10.1245/s10434-016-5205-4. Epub 2016 Mar 28. Ann Surg Oncol. 2016. PMID: 27020587 Free PMC article. Clinical Trial.
Radiogenomics of rectal adenocarcinoma in the era of precision medicine: A pilot study of associations between qualitative and quantitative MRI imaging features and genetic mutations.
Horvat N, Veeraraghavan H, Pelossof RA, Fernandes MC, Arora A, Khan M, Marco M, Cheng CT, Gonen M, Golia Pernicka JS, Gollub MJ, Garcia-Aguillar J, Petkovska I. Horvat N, et al. Among authors: pelossof ra. Eur J Radiol. 2019 Apr;113:174-181. doi: 10.1016/j.ejrad.2019.02.022. Epub 2019 Feb 18. Eur J Radiol. 2019. PMID: 30927944 Free PMC article.
Consolidation mFOLFOX6 Chemotherapy After Chemoradiotherapy Improves Survival in Patients With Locally Advanced Rectal Cancer: Final Results of a Multicenter Phase II Trial.
Marco MR, Zhou L, Patil S, Marcet JE, Varma MG, Oommen S, Cataldo PA, Hunt SR, Kumar A, Herzig DO, Fichera A, Polite BN, Hyman NH, Ternent CA, Stamos MJ, Pigazzi A, Dietz D, Yakunina Y, Pelossof R, Garcia-Aguilar J; Timing of Rectal Cancer Response to Chemoradiation Consortium. Marco MR, et al. Among authors: pelossof r. Dis Colon Rectum. 2018 Oct;61(10):1146-1155. doi: 10.1097/DCR.0000000000001207. Dis Colon Rectum. 2018. PMID: 30192323 Free PMC article. Clinical Trial.
Prediction of potent shRNAs with a sequential classification algorithm.
Pelossof R, Fairchild L, Huang CH, Widmer C, Sreedharan VT, Sinha N, Lai DY, Guan Y, Premsrirut PK, Tschaharganeh DF, Hoffmann T, Thapar V, Xiang Q, Garippa RJ, Rätsch G, Zuber J, Lowe SW, Leslie CS, Fellmann C. Pelossof R, et al. Nat Biotechnol. 2017 Apr;35(4):350-353. doi: 10.1038/nbt.3807. Epub 2017 Mar 6. Nat Biotechnol. 2017. PMID: 28263295 Free PMC article.
19 results