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Chromothripsis as an on-target consequence of CRISPR-Cas9 genome editing.
Leibowitz ML, Papathanasiou S, Doerfler PA, Blaine LJ, Sun L, Yao Y, Zhang CZ, Weiss MJ, Pellman D. Leibowitz ML, et al. Among authors: pellman d. Nat Genet. 2021 Jun;53(6):895-905. doi: 10.1038/s41588-021-00838-7. Epub 2021 Apr 12. Nat Genet. 2021. PMID: 33846636 Free PMC article.
Tetraploidy, aneuploidy and cancer.
Ganem NJ, Storchova Z, Pellman D. Ganem NJ, et al. Among authors: pellman d. Curr Opin Genet Dev. 2007 Apr;17(2):157-62. doi: 10.1016/j.gde.2007.02.011. Epub 2007 Feb 26. Curr Opin Genet Dev. 2007. PMID: 17324569 Review.
DNA breaks and chromosome pulverization from errors in mitosis.
Crasta K, Ganem NJ, Dagher R, Lantermann AB, Ivanova EV, Pan Y, Nezi L, Protopopov A, Chowdhury D, Pellman D. Crasta K, et al. Among authors: pellman d. Nature. 2012 Jan 18;482(7383):53-8. doi: 10.1038/nature10802. Nature. 2012. PMID: 22258507 Free PMC article.
Causes and consequences of aneuploidy in cancer.
Gordon DJ, Resio B, Pellman D. Gordon DJ, et al. Among authors: pellman d. Nat Rev Genet. 2012 Jan 24;13(3):189-203. doi: 10.1038/nrg3123. Nat Rev Genet. 2012. PMID: 22269907 Review.
Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation.
Lane AA, Chapuy B, Lin CY, Tivey T, Li H, Townsend EC, van Bodegom D, Day TA, Wu SC, Liu H, Yoda A, Alexe G, Schinzel AC, Sullivan TJ, Malinge S, Taylor JE, Stegmaier K, Jaffe JD, Bustin M, te Kronnie G, Izraeli S, Harris MH, Stevenson KE, Neuberg D, Silverman LB, Sallan SE, Bradner JE, Hahn WC, Crispino JD, Pellman D, Weinstock DM. Lane AA, et al. Among authors: pellman d. Nat Genet. 2014 Jun;46(6):618-23. doi: 10.1038/ng.2949. Epub 2014 Apr 20. Nat Genet. 2014. PMID: 24747640 Free PMC article.
Chromothripsis from DNA damage in micronuclei.
Zhang CZ, Spektor A, Cornils H, Francis JM, Jackson EK, Liu S, Meyerson M, Pellman D. Zhang CZ, et al. Among authors: pellman d. Nature. 2015 Jun 11;522(7555):179-84. doi: 10.1038/nature14493. Epub 2015 May 27. Nature. 2015. PMID: 26017310 Free PMC article.
Chromothripsis: A New Mechanism for Rapid Karyotype Evolution.
Leibowitz ML, Zhang CZ, Pellman D. Leibowitz ML, et al. Among authors: pellman d. Annu Rev Genet. 2015;49:183-211. doi: 10.1146/annurev-genet-120213-092228. Epub 2015 Oct 6. Annu Rev Genet. 2015. PMID: 26442848 Review.
124 results