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Early evolutionary loss of the lipid A modifying enzyme PagP resulting in innate immune evasion in Yersinia pestis.
Chandler CE, Harberts EM, Pelletier MR, Thaipisuttikul I, Jones JW, Hajjar AM, Sahl JW, Goodlett DR, Pride AC, Rasko DA, Trent MS, Bishop RE, Ernst RK. Chandler CE, et al. Among authors: pelletier mr. Proc Natl Acad Sci U S A. 2020 Sep 15;117(37):22984-22991. doi: 10.1073/pnas.1917504117. Epub 2020 Aug 31. Proc Natl Acad Sci U S A. 2020. PMID: 32868431 Free PMC article.
LPS remodeling is an evolved survival strategy for bacteria.
Li Y, Powell DA, Shaffer SA, Rasko DA, Pelletier MR, Leszyk JD, Scott AJ, Masoudi A, Goodlett DR, Wang X, Raetz CR, Ernst RK. Li Y, et al. Proc Natl Acad Sci U S A. 2012 May 29;109(22):8716-21. doi: 10.1073/pnas.1202908109. Epub 2012 May 14. Proc Natl Acad Sci U S A. 2012. PMID: 22586119 Free PMC article.
Rationally Designed TLR4 Ligands for Vaccine Adjuvant Discovery.
Gregg KA, Harberts E, Gardner FM, Pelletier MR, Cayatte C, Yu L, McCarthy MP, Marshall JD, Ernst RK. Gregg KA, et al. Among authors: pelletier mr. mBio. 2017 May 9;8(3):e00492-17. doi: 10.1128/mBio.00492-17. mBio. 2017. PMID: 28487429 Free PMC article.
813 results