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Bactericidal Disruption of Magnesium Metallostasis in Mycobacterium tuberculosis Is Counteracted by Mutations in the Metal Ion Transporter CorA.
Lopez Quezada L, Silve S, Kelinske M, Liba A, Diaz Gonzalez C, Kotev M, Goullieux L, Sans S, Roubert C, Lagrange S, Bacqué E, Couturier C, Pellet A, Blanc I, Ferron M, Debu F, Li K, Aubé J, Roberts J, Little D, Ling Y, Zhang J, Gold B, Nathan C. Lopez Quezada L, et al. Among authors: pellet a. mBio. 2019 Jul 9;10(4):e01405-19. doi: 10.1128/mBio.01405-19. mBio. 2019. PMID: 31289182 Free PMC article.
Identification and optimization of a new series of anti-tubercular quinazolinones.
Couturier C, Lair C, Pellet A, Upton A, Kaneko T, Perron C, Cogo E, Menegotto J, Bauer A, Scheiper B, Lagrange S, Bacqué E. Couturier C, et al. Among authors: pellet a. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5290-5299. doi: 10.1016/j.bmcl.2016.09.043. Epub 2016 Sep 16. Bioorg Med Chem Lett. 2016. PMID: 27671498
The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance.
Murithi JM, Pascal C, Bath J, Boulenc X, Gnädig NF, Pasaje CFA, Rubiano K, Yeo T, Mok S, Klieber S, Desert P, Jiménez-Díaz MB, Marfurt J, Rouillier M, Cherkaoui-Rbati MH, Gobeau N, Wittlin S, Uhlemann AC, Price RN, Wirjanata G, Noviyanti R, Tumwebaze P, Cooper RA, Rosenthal PJ, Sanz LM, Gamo FJ, Joseph J, Singh S, Bashyam S, Augereau JM, Giraud E, Bozec T, Vermat T, Tuffal G, Guillon JM, Menegotto J, Sallé L, Louit G, Cabanis MJ, Nicolas MF, Doubovetzky M, Merino R, Bessila N, Angulo-Barturen I, Baud D, Bebrevska L, Escudié F, Niles JC, Blasco B, Campbell S, Courtemanche G, Fraisse L, Pellet A, Fidock DA, Leroy D. Murithi JM, et al. Among authors: pellet a. Sci Transl Med. 2021 Jul 21;13(603):eabg6013. doi: 10.1126/scitranslmed.abg6013. Sci Transl Med. 2021. PMID: 34290058 Free PMC article.
SR 120819A, an orally-active and selective neuropeptide Y Y1 receptor antagonist.
Serradeil-Le Gal C, Valette G, Rouby PE, Pellet A, Oury-Donat F, Brossard G, Lespy L, Marty E, Neliat G, de Cointet P, et al. Serradeil-Le Gal C, et al. Among authors: pellet a. FEBS Lett. 1995 Apr 3;362(2):192-6. doi: 10.1016/0014-5793(95)00230-7. FEBS Lett. 1995. PMID: 7720871 Free article.
In vitro activity of ferroquine against artemisinin-based combination therapy (ACT)-resistant Plasmodium falciparum isolates from Cambodia.
Mairet-Khedim M, Nardella F, Khim N, Kim S, Kloeung N, Ke S, Kauy C, Eam R, Khean C, Pellet A, Leboulleux D, Leang R, Ringwald P, Barale JC, Leroy D, Menard D, Witkowski B. Mairet-Khedim M, et al. Among authors: pellet a. J Antimicrob Chemother. 2019 Nov 1;74(11):3240-3244. doi: 10.1093/jac/dkz340. J Antimicrob Chemother. 2019. PMID: 31518407
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