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Successive crystal structure snapshots suggest the basis for MHC class I peptide loading and editing by tapasin.
Hafstrand I, Sayitoglu EC, Apavaloaei A, Josey BJ, Sun R, Han X, Pellegrino S, Ozkazanc D, Potens R, Janssen L, Nilvebrant J, Nygren PÅ, Sandalova T, Springer S, Georgoudaki AM, Duru AD, Achour A. Hafstrand I, et al. Among authors: pellegrino s. Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):5055-5060. doi: 10.1073/pnas.1807656116. Epub 2019 Feb 26. Proc Natl Acad Sci U S A. 2019. PMID: 30808808 Free PMC article.
Class I major histocompatibility complex, the trojan horse for secretion of amyloidogenic β2-microglobulin.
Halabelian L, Ricagno S, Giorgetti S, Santambrogio C, Barbiroli A, Pellegrino S, Achour A, Grandori R, Marchese L, Raimondi S, Mangione PP, Esposito G, Al-Shawi R, Simons JP, Speck I, Stoppini M, Bolognesi M, Bellotti V. Halabelian L, et al. Among authors: pellegrino s. J Biol Chem. 2014 Feb 7;289(6):3318-27. doi: 10.1074/jbc.M113.524157. Epub 2013 Dec 13. J Biol Chem. 2014. PMID: 24338476 Free PMC article.
Crystal structures of H-2Db in complex with the LCMV-derived peptides GP92 and GP392 explain pleiotropic effects of glycosylation on antigen presentation and immunogenicity.
Hafstrand I, Badia-Martinez D, Josey BJ, Norström M, Buratto J, Pellegrino S, Duru AD, Sandalova T, Achour A. Hafstrand I, et al. Among authors: pellegrino s. PLoS One. 2017 Dec 18;12(12):e0189584. doi: 10.1371/journal.pone.0189584. eCollection 2017. PLoS One. 2017. PMID: 29253009 Free PMC article.
Memory T cells specific to citrullinated α-enolase are enriched in the rheumatic joint.
Pieper J, Dubnovitsky A, Gerstner C, James EA, Rieck M, Kozhukh G, Tandre K, Pellegrino S, Gebe JA, Rönnblom L, Sandalova T, Kwok WW, Klareskog L, Buckner JH, Achour A, Malmström V. Pieper J, et al. Among authors: pellegrino s. J Autoimmun. 2018 Aug;92:47-56. doi: 10.1016/j.jaut.2018.04.004. Epub 2018 May 28. J Autoimmun. 2018. PMID: 29853344 Free PMC article.
Tuning antiviral CD8 T-cell response via proline-altered peptide ligand vaccination.
Duru AD, Sun R, Allerbring EB, Chadderton J, Kadri N, Han X, Peqini K, Uchtenhagen H, Madhurantakam C, Pellegrino S, Sandalova T, Nygren PÅ, Turner SJ, Achour A. Duru AD, et al. Among authors: pellegrino s. PLoS Pathog. 2020 May 4;16(5):e1008244. doi: 10.1371/journal.ppat.1008244. eCollection 2020 May. PLoS Pathog. 2020. PMID: 32365082 Free PMC article.
l- to d-Amino Acid Substitution in the Immunodominant LCMV-Derived Epitope gp33 Highlights the Sensitivity of the TCR Recognition Mechanism for the MHC/Peptide Structure and Dynamics.
Ballabio F, Broggini L, Paissoni C, Han X, Peqini K, Sala BM, Sun R, Sandalova T, Barbiroli A, Achour A, Pellegrino S, Ricagno S, Camilloni C. Ballabio F, et al. Among authors: pellegrino s. ACS Omega. 2022 Mar 7;7(11):9622-9635. doi: 10.1021/acsomega.1c06964. eCollection 2022 Mar 22. ACS Omega. 2022. PMID: 35350306 Free PMC article.
Multi-eGO: An in silico lens to look into protein aggregation kinetics at atomic resolution.
Scalone E, Broggini L, Visentin C, Erba D, Bačić Toplek F, Peqini K, Pellegrino S, Ricagno S, Paissoni C, Camilloni C. Scalone E, et al. Among authors: pellegrino s. Proc Natl Acad Sci U S A. 2022 Jun 28;119(26):e2203181119. doi: 10.1073/pnas.2203181119. Epub 2022 Jun 23. Proc Natl Acad Sci U S A. 2022. PMID: 35737839 Free PMC article.
236 results