Pellegrini S - Search Results

1

The Stat3-activating Tyk2 V678F mutant does not up-regulate signaling through the type I interferon receptor but confers ligand hypersensitivity to a homodimeric receptor.

Gakovic M, Ragimbeau J, Francois V, Constantinescu SN, Pellegrini S. Gakovic M, et al. Among authors: pellegrini s. J Biol Chem. 2008 Jul 4;283(27):18522-9. doi: 10.1074/jbc.M801427200. Epub 2008 May 2. J Biol Chem. 2008. PMID: 18456658 Free article.

2

Jamip1 (marlin-1) defines a family of proteins interacting with janus kinases and microtubules.

Steindler C, Li Z, Algarté M, Alcover A, Libri V, Ragimbeau J, Pellegrini S. Steindler C, et al. Among authors: pellegrini s. J Biol Chem. 2004 Oct 8;279(41):43168-77. doi: 10.1074/jbc.M401915200. Epub 2004 Jul 23. J Biol Chem. 2004. PMID: 15277531 Free article.

3

TYK2 activity promotes ligand-induced IFNAR1 proteolysis.

Marijanovic Z, Ragimbeau J, Kumar KG, Fuchs SY, Pellegrini S. Marijanovic Z, et al. Among authors: pellegrini s. Biochem J. 2006 Jul 1;397(1):31-8. doi: 10.1042/BJ20060272. Biochem J. 2006. PMID: 16551269 Free PMC article.

4

Basal ubiquitin-independent internalization of interferon alpha receptor is prevented by Tyk2-mediated masking of a linear endocytic motif.

Kumar KG, Varghese B, Banerjee A, Baker DP, Constantinescu SN, Pellegrini S, Fuchs SY. Kumar KG, et al. Among authors: pellegrini s. J Biol Chem. 2008 Jul 4;283(27):18566-72. doi: 10.1074/jbc.M800991200. Epub 2008 May 12. J Biol Chem. 2008. PMID: 18474601 Free PMC article.

5

Two rare disease-associated Tyk2 variants are catalytically impaired but signaling competent.

Li Z, Gakovic M, Ragimbeau J, Eloranta ML, Rönnblom L, Michel F, Pellegrini S. Li Z, et al. Among authors: pellegrini s. J Immunol. 2013 Mar 1;190(5):2335-44. doi: 10.4049/jimmunol.1203118. Epub 2013 Jan 28. J Immunol. 2013. PMID: 23359498

6

The receptor interaction region of Tyk2 contains a motif required for its nuclear localization.

Ragimbeau J, Dondi E, Vasserot A, Romero P, Uzé G, Pellegrini S. Ragimbeau J, et al. Among authors: pellegrini s. J Biol Chem. 2001 Aug 17;276(33):30812-8. doi: 10.1074/jbc.M103559200. Epub 2001 Jun 8. J Biol Chem. 2001. PMID: 11399767 Free article.

7

The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.

Ragimbeau J, Dondi E, Alcover A, Eid P, Uzé G, Pellegrini S. Ragimbeau J, et al. Among authors: pellegrini s. EMBO J. 2003 Feb 3;22(3):537-47. doi: 10.1093/emboj/cdg038. EMBO J. 2003. PMID: 12554654 Free PMC article.

8

Comparable potency of IFNalpha2 and IFNbeta on immediate JAK/STAT activation but differential down-regulation of IFNAR2.

Marijanovic Z, Ragimbeau J, van der Heyden J, Uzé G, Pellegrini S. Marijanovic Z, et al. Among authors: pellegrini s. Biochem J. 2007 Oct 1;407(1):141-51. doi: 10.1042/BJ20070605. Biochem J. 2007. PMID: 17627610 Free PMC article.

9

Ligand-independent pathway that controls stability of interferon alpha receptor.

Liu J, Plotnikov A, Banerjee A, Suresh Kumar KG, Ragimbeau J, Marijanovic Z, Baker DP, Pellegrini S, Fuchs SY. Liu J, et al. Among authors: pellegrini s. Biochem Biophys Res Commun. 2008 Mar 7;367(2):388-93. doi: 10.1016/j.bbrc.2007.12.137. Epub 2007 Dec 31. Biochem Biophys Res Commun. 2008. PMID: 18166147 Free PMC article.

10

Jakmip1 is expressed upon T cell differentiation and has an inhibitory function in cytotoxic T lymphocytes.

Libri V, Schulte D, van Stijn A, Ragimbeau J, Rogge L, Pellegrini S. Libri V, et al. Among authors: pellegrini s. J Immunol. 2008 Nov 1;181(9):5847-56. doi: 10.4049/jimmunol.181.9.5847. J Immunol. 2008. PMID: 18941173

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