Pekrun K - Search Results

1

AAV-mediated genome editing is influenced by the formation of R-loops.

Puzzo F, Crossley MP, Goswami A, Zhang F, Pekrun K, Garzon JL, Cimprich KA, Kay MA. Puzzo F, et al. Among authors: pekrun k. bioRxiv [Preprint]. 2024 May 9:2024.05.07.592855. doi: 10.1101/2024.05.07.592855. bioRxiv. 2024. PMID: 38766176 Free PMC article. Preprint.

2

Correlation of antigen expression with epigenetic modifications after rAAV delivery of a human factor IX variant in mice and rhesus macaques.

Pekrun K, Stephens CJ, Gonzalez-Sandoval A, Goswami A, Zhang F, Tarantal AF, Blouse G, Kay MA. Pekrun K, et al. Mol Ther. 2024 May 7:S1525-0016(24)00306-X. doi: 10.1016/j.ymthe.2024.05.005. Online ahead of print. Mol Ther. 2024. PMID: 38715361

3

Genome engineering with Cas9 and AAV repair templates generates frequent concatemeric insertions of viral vectors.

Suchy FP, Karigane D, Nakauchi Y, Higuchi M, Zhang J, Pekrun K, Hsu I, Fan AC, Nishimura T, Charlesworth CT, Bhadury J, Nishimura T, Wilkinson AC, Kay MA, Majeti R, Nakauchi H. Suchy FP, et al. Among authors: pekrun k. Nat Biotechnol. 2024 Apr 8. doi: 10.1038/s41587-024-02171-w. Online ahead of print. Nat Biotechnol. 2024. PMID: 38589662

4

Selection of viral capsids and promoters affects the efficacy of rescue of Tmprss3-deficient cochlea.

Aaron KA, Pekrun K, Atkinson PJ, Billings SE, Abitbol JM, Lee IA, Eltawil Y, Chen YS, Dong W, Nelson RF, Kay MA, Cheng AG. Aaron KA, et al. Among authors: pekrun k. Mol Ther Methods Clin Dev. 2023 Aug 11;30:413-428. doi: 10.1016/j.omtm.2023.08.004. eCollection 2023 Sep 14. Mol Ther Methods Clin Dev. 2023. PMID: 37663645 Free PMC article.

5

A strategy for high antibody expression with low anti-drug antibodies using AAV9 vectors.

Davis-Gardner ME, Weber JA, Xie J, Pekrun K, Alexander EA, Weisgrau KL, Furlott JR, Rakasz EG, Kay MA, Gao G, Farzan M, Gardner MR. Davis-Gardner ME, et al. Among authors: pekrun k. Front Immunol. 2023 Apr 21;14:1105617. doi: 10.3389/fimmu.2023.1105617. eCollection 2023. Front Immunol. 2023. PMID: 37153616 Free PMC article.

6

The AAV capsid can influence the epigenetic marking of rAAV delivered episomal genomes in a species dependent manner.

Gonzalez-Sandoval A, Pekrun K, Tsuji S, Zhang F, Hung KL, Chang HY, Kay MA. Gonzalez-Sandoval A, et al. Among authors: pekrun k. Nat Commun. 2023 Apr 28;14(1):2448. doi: 10.1038/s41467-023-38106-3. Nat Commun. 2023. PMID: 37117181 Free PMC article.

7

Selection of rAAV vectors that cross the human blood-brain barrier and target the central nervous system using a transwell model.

Song R, Pekrun K, Khan TA, Zhang F, Paşca SP, Kay MA. Song R, et al. Among authors: pekrun k. Mol Ther Methods Clin Dev. 2022 Sep 7;27:73-88. doi: 10.1016/j.omtm.2022.09.002. eCollection 2022 Dec 8. Mol Ther Methods Clin Dev. 2022. PMID: 36186955 Free PMC article.

8

Fludarabine increases nuclease-free AAV- and CRISPR/Cas9-mediated homologous recombination in mice.

Tsuji S, Stephens CJ, Bortolussi G, Zhang F, Baj G, Jang H, de Alencastro G, Muro AF, Pekrun K, Kay MA. Tsuji S, et al. Among authors: pekrun k. Nat Biotechnol. 2022 Aug;40(8):1285-1294. doi: 10.1038/s41587-022-01240-2. Epub 2022 Apr 7. Nat Biotechnol. 2022. PMID: 35393561

9

Improved Genome Editing through Inhibition of FANCM and Members of the BTR Dissolvase Complex.

de Alencastro G, Puzzo F, Pavel-Dinu M, Zhang F, Pillay S, Majzoub K, Tiffany M, Jang H, Sheikali A, Cromer MK, Meetei R, Carette JE, Porteus MH, Pekrun K, Kay MA. de Alencastro G, et al. Among authors: pekrun k. Mol Ther. 2021 Mar 3;29(3):1016-1027. doi: 10.1016/j.ymthe.2020.10.020. Epub 2020 Oct 22. Mol Ther. 2021. PMID: 33678249 Free PMC article.

10

Tracking Adeno-Associated Virus Capsid Evolution by High-Throughput Sequencing.

de Alencastro G, Pekrun K, Valdmanis P, Tiffany M, Xu J, Kay MA. de Alencastro G, et al. Among authors: pekrun k. Hum Gene Ther. 2020 May;31(9-10):553-564. doi: 10.1089/hum.2019.339. Epub 2020 Mar 5. Hum Gene Ther. 2020. PMID: 32024384 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

20 results

Search Page