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A SARS-CoV-2 spike ferritin nanoparticle vaccine protects against heterologous challenge with B.1.1.7 and B.1.351 virus variants in Syrian golden hamsters.
Wuertz KM, Barkei EK, Chen WH, Martinez EJ, Lakhal-Naouar I, Jagodzinski LL, Paquin-Proulx D, Gromowski GD, Swafford I, Ganesh A, Dong M, Zeng X, Thomas PV, Sankhala RS, Hajduczki A, Peterson CE, Kuklis C, Soman S, Wieczorek L, Zemil M, Anderson A, Darden J, Hernandez H, Grove H, Dussupt V, Hack H, de la Barrera R, Zarling S, Wood JF, Froude JW, Gagne M, Henry AR, Mokhtari EB, Mudvari P, Krebs SJ, Pekosz AS, Currier JR, Kar S, Porto M, Winn A, Radzyminski K, Lewis MG, Vasan S, Suthar M, Polonis VR, Matyas GR, Boritz EA, Douek DC, Seder RA, Daye SP, Rao M, Peel SA, Joyce MG, Bolton DL, Michael NL, Modjarrad K. Wuertz KM, et al. Among authors: pekosz as. bioRxiv [Preprint]. 2021 Jun 16:2021.06.16.448525. doi: 10.1101/2021.06.16.448525. bioRxiv. 2021. PMID: 34159328 Free PMC article. Updated. Preprint.
Highly multiplexed oligonucleotide probe-ligation testing enables efficient extraction-free SARS-CoV-2 detection and viral genotyping.
Credle JJ, Robinson ML, Gunn J, Monaco D, Sie B, Tchir A, Hardick J, Zheng X, Shaw-Saliba K, Rothman RE, Eshleman SH, Pekosz A, Hansen K, Mostafa H, Steinegger M, Larman HB. Credle JJ, et al. bioRxiv [Preprint]. 2020 Jun 3:2020.06.03.130591. doi: 10.1101/2020.06.03.130591. bioRxiv. 2020. PMID: 32577648 Free PMC article. Updated. Preprint.
CD8+ T cell responses in convalescent COVID-19 individuals target epitopes from the entire SARS-CoV-2 proteome and show kinetics of early differentiation.
Kared H, Redd AD, Bloch EM, Bonny TS, Sumatoh H, Kairi F, Carbajo D, Abel B, Newell EW, Bettinotti MP, Benner SE, Patel EU, Littlefield K, Laeyendecker O, Shoham S, Sullivan D, Casadevall A, Pekosz A, Nardin A, Fehlings M, Tobian AA, Quinn TC. Kared H, et al. bioRxiv [Preprint]. 2020 Oct 8:2020.10.08.330688. doi: 10.1101/2020.10.08.330688. bioRxiv. 2020. PMID: 33052343 Free PMC article. Preprint.
Durable SARS-CoV-2 B cell immunity after mild or severe disease.
Ogega CO, Skinner NE, Blair PW, Park HS, Littlefield K, Ganesan A, Ladiwala P, Antar AA, Ray SC, Betenbaugh MJ, Pekosz A, Klein SL, Manabe YC, Cox AL, Bailey JR. Ogega CO, et al. medRxiv [Preprint]. 2020 Oct 30:2020.10.28.20220996. doi: 10.1101/2020.10.28.20220996. medRxiv. 2020. PMID: 33140070 Free PMC article. Updated. Preprint.
Comparative performance of multiplex salivary and commercially available serologic assays to detect SARS-CoV-2 IgG and neutralization titers.
Heaney CD, Pisanic N, Randad PR, Kruczynski K, Howard T, Zhu X, Littlefield K, Patel EU, Shrestha R, Laeyendecker O, Shoham S, Sullivan D, Gebo K, Hanley D, Redd AD, Quinn TC, Casadevall A, Zenilman JM, Pekosz A, Bloch EM, Tobian AAR. Heaney CD, et al. medRxiv [Preprint]. 2021 Feb 1:2021.01.28.21250717. doi: 10.1101/2021.01.28.21250717. medRxiv. 2021. PMID: 33532806 Free PMC article. Updated. Preprint.
Sex differences in lung imaging and SARS-CoV-2 antibody responses in a COVID-19 golden Syrian hamster model.
Dhakal S, Ruiz-Bedoya CA, Zhou R, Creisher P, Villano J, Littlefield K, Castillo J, Marinho P, Jedlicka A, Ordonez A, Majewska N, Betenbaugh M, Flavahan K, Mueller A, Looney M, Quijada D, Mota F, Beck SE, Brockhurst JK, Braxton A, Castell N, D'Alessio F, Metcalf Pate KA, Karakousis PC, Mankowski JL, Pekosz A, Jain SK, Klein SL. Dhakal S, et al. bioRxiv [Preprint]. 2021 Apr 4:2021.04.02.438292. doi: 10.1101/2021.04.02.438292. bioRxiv. 2021. PMID: 33821269 Free PMC article. Updated. Preprint.
Sex Differences in Lung Imaging and SARS-CoV-2 Antibody Responses in a COVID-19 Golden Syrian Hamster Model.
Dhakal S, Ruiz-Bedoya CA, Zhou R, Creisher PS, Villano JS, Littlefield K, Ruelas Castillo J, Marinho P, Jedlicka AE, Ordonez AA, Bahr M, Majewska N, Betenbaugh MJ, Flavahan K, Mueller ARL, Looney MM, Quijada D, Mota F, Beck SE, Brockhurst J, Braxton AM, Castell N, Stover M, D'Alessio FR, Metcalf Pate KA, Karakousis PC, Mankowski JL, Pekosz A, Jain SK, Klein SL; Johns Hopkins COVID-19 Hamster Study Group. Dhakal S, et al. mBio. 2021 Aug 31;12(4):e0097421. doi: 10.1128/mBio.00974-21. Epub 2021 Jul 13. mBio. 2021. PMID: 34253053 Free PMC article.
219 results