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GLS-driven glutamine catabolism contributes to prostate cancer radiosensitivity by regulating the redox state, stemness and ATG5-mediated autophagy.
Mukha A, Kahya U, Linge A, Chen O, Löck S, Lukiyanchuk V, Richter S, Alves TC, Peitzsch M, Telychko V, Skvortsov S, Negro G, Aschenbrenner B, Skvortsova II, Mirtschink P, Lohaus F, Hölscher T, Neubauer H, Rivandi M, Labitzky V, Lange T, Franken A, Behrens B, Stoecklein NH, Toma M, Sommer U, Zschaeck S, Rehm M, Eisenhofer G, Schwager C, Abdollahi A, Groeben C, Kunz-Schughart LA, Baretton GB, Baumann M, Krause M, Peitzsch C, Dubrovska A. Mukha A, et al. Among authors: peitzsch c. Theranostics. 2021 Jun 26;11(16):7844-7868. doi: 10.7150/thno.58655. eCollection 2021. Theranostics. 2021. PMID: 34335968 Free PMC article.
The CD98 Heavy Chain Is a Marker and Regulator of Head and Neck Squamous Cell Carcinoma Radiosensitivity.
Digomann D, Kurth I, Tyutyunnykova A, Chen O, Löck S, Gorodetska I, Peitzsch C, Skvortsova II, Negro G, Aschenbrenner B, Eisenhofer G, Richter S, Heiden S, Porrmann J, Klink B, Schwager C, Dowle AA, Hein L, Kunz-Schughart LA, Abdollahi A, Lohaus F, Krause M, Baumann M, Linge A, Dubrovska A. Digomann D, et al. Among authors: peitzsch c. Clin Cancer Res. 2019 May 15;25(10):3152-3163. doi: 10.1158/1078-0432.CCR-18-2951. Epub 2019 Jan 22. Clin Cancer Res. 2019. PMID: 30670494
Cellular plasticity upon proton irradiation determines tumor cell radiosensitivity.
Schniewind I, Hadiwikarta WW, Grajek J, Poleszczuk J, Richter S, Peitzsch M, Müller J, Klusa D, Beyreuther E, Löck S, Lühr A, Frosch S, Groeben C, Sommer U, Krause M, Dubrovska A, von Neubeck C, Kurth I, Peitzsch C. Schniewind I, et al. Among authors: peitzsch c. Cell Rep. 2022 Feb 22;38(8):110422. doi: 10.1016/j.celrep.2022.110422. Cell Rep. 2022. PMID: 35196495 Free article.
Hypoxia as a biomarker for radioresistant cancer stem cells.
Peitzsch C, Perrin R, Hill RP, Dubrovska A, Kurth I. Peitzsch C, et al. Int J Radiat Biol. 2014 Aug;90(8):636-52. doi: 10.3109/09553002.2014.916841. Epub 2014 Jun 25. Int J Radiat Biol. 2014. PMID: 24844374 Review.
Aldehyde Dehydrogenase Is Regulated by β-Catenin/TCF and Promotes Radioresistance in Prostate Cancer Progenitor Cells.
Cojoc M, Peitzsch C, Kurth I, Trautmann F, Kunz-Schughart LA, Telegeev GD, Stakhovsky EA, Walker JR, Simin K, Lyle S, Fuessel S, Erdmann K, Wirth MP, Krause M, Baumann M, Dubrovska A. Cojoc M, et al. Among authors: peitzsch c. Cancer Res. 2015 Apr 1;75(7):1482-94. doi: 10.1158/0008-5472.CAN-14-1924. Epub 2015 Feb 10. Cancer Res. 2015. PMID: 25670168
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