Peifer C - Search Results

1

The CK1 Family: Contribution to Cellular Stress Response and Its Role in Carcinogenesis.

Knippschild U, Krüger M, Richter J, Xu P, García-Reyes B, Peifer C, Halekotte J, Bakulev V, Bischof J. Knippschild U, et al. Among authors: peifer c. Front Oncol. 2014 May 19;4:96. doi: 10.3389/fonc.2014.00096. eCollection 2014. Front Oncol. 2014. PMID: 24904820 Free PMC article. Review.

2

3,4-Diaryl-isoxazoles and -imidazoles as potent dual inhibitors of p38alpha mitogen activated protein kinase and casein kinase 1delta.

Peifer C, Abadleh M, Bischof J, Hauser D, Schattel V, Hirner H, Knippschild U, Laufer S. Peifer C, et al. J Med Chem. 2009 Dec 10;52(23):7618-30. doi: 10.1021/jm9005127. J Med Chem. 2009. PMID: 19591487

3

Impaired CK1 delta activity attenuates SV40-induced cellular transformation in vitro and mouse mammary carcinogenesis in vivo.

Hirner H, Günes C, Bischof J, Wolff S, Grothey A, Kühl M, Oswald F, Wegwitz F, Bösl MR, Trauzold A, Henne-Bruns D, Peifer C, Leithäuser F, Deppert W, Knippschild U. Hirner H, et al. Among authors: peifer c. PLoS One. 2012;7(1):e29709. doi: 10.1371/journal.pone.0029709. Epub 2012 Jan 3. PLoS One. 2012. PMID: 22235331 Free PMC article.

4

Effects of altered expression and activity levels of CK1δ and ɛ on tumor growth and survival of colorectal cancer patients.

Richter J, Ullah K, Xu P, Alscher V, Blatz A, Peifer C, Halekotte J, Leban J, Vitt D, Holzmann K, Bakulev V, Pinna LA, Henne-Bruns D, Hillenbrand A, Kornmann M, Leithäuser F, Bischof J, Knippschild U. Richter J, et al. Among authors: peifer c. Int J Cancer. 2015 Jun 15;136(12):2799-810. doi: 10.1002/ijc.29346. Epub 2014 Dec 1. Int J Cancer. 2015. PMID: 25404202 Free article.

5

State-dependent block of voltage-gated sodium channels by the casein-kinase 1 inhibitor IC261.

Föhr KJ, Knippschild U, Herkommer A, Fauler M, Peifer C, Georgieff M, Adolph O. Föhr KJ, et al. Among authors: peifer c. Invest New Drugs. 2017 Jun;35(3):277-289. doi: 10.1007/s10637-017-0429-0. Epub 2017 Feb 6. Invest New Drugs. 2017. PMID: 28164251

6

Optimized 4,5-Diarylimidazoles as Potent/Selective Inhibitors of Protein Kinase CK1δ and Their Structural Relation to p38α MAPK.

Halekotte J, Witt L, Ianes C, Krüger M, Bührmann M, Rauh D, Pichlo C, Brunstein E, Luxenburger A, Baumann U, Knippschild U, Bischof J, Peifer C. Halekotte J, et al. Among authors: peifer c. Molecules. 2017 Mar 24;22(4):522. doi: 10.3390/molecules22040522. Molecules. 2017. PMID: 28338621 Free PMC article.

7

A CK1 FRET biosensor reveals that DDX3X is an essential activator of CK1ε.

Dolde C, Bischof J, Grüter S, Montada A, Halekotte J, Peifer C, Kalbacher H, Baumann U, Knippschild U, Suter B. Dolde C, et al. Among authors: peifer c. J Cell Sci. 2018 Jan 4;131(1):jcs207316. doi: 10.1242/jcs.207316. J Cell Sci. 2018. PMID: 29222110 Free PMC article.

8

Discovery of Inhibitor of Wnt Production 2 (IWP-2) and Related Compounds As Selective ATP-Competitive Inhibitors of Casein Kinase 1 (CK1) δ/ε.

García-Reyes B, Witt L, Jansen B, Karasu E, Gehring T, Leban J, Henne-Bruns D, Pichlo C, Brunstein E, Baumann U, Wesseler F, Rathmer B, Schade D, Peifer C, Knippschild U. García-Reyes B, et al. Among authors: peifer c. J Med Chem. 2018 May 10;61(9):4087-4102. doi: 10.1021/acs.jmedchem.8b00095. Epub 2018 May 1. J Med Chem. 2018. PMID: 29630366

9

Design, Synthesis and Biological Evaluation of Isoxazole-Based CK1 Inhibitors Modified with Chiral Pyrrolidine Scaffolds.

Luxenburger A, Schmidt D, Ianes C, Pichlo C, Krüger M, von Drathen T, Brunstein E, Gainsford GJ, Baumann U, Knippschild U, Peifer C. Luxenburger A, et al. Among authors: peifer c. Molecules. 2019 Mar 1;24(5):873. doi: 10.3390/molecules24050873. Molecules. 2019. PMID: 30832206 Free PMC article.

10

2-Azo-, 2-diazocine-thiazols and 2-azo-imidazoles as photoswitchable kinase inhibitors: limitations and pitfalls of the photoswitchable inhibitor approach.

Schehr M , Ianes C , Weisner J , Heintze L , Müller MP , Pichlo C , Charl J , Brunstein E , Ewert J , Lehr M , Baumann U , Rauh D , Knippschild U , Peifer C , Herges R . Schehr M , et al. Among authors: peifer c. Photochem Photobiol Sci. 2019 Jun 12;18(6):1398-1407. doi: 10.1039/c9pp00010k. Photochem Photobiol Sci. 2019. PMID: 30924488

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