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Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling.
Chem Sci. 2021 Nov 25;12(48):15975-15987. doi: 10.1039/d1sc05187c. eCollection 2021 Dec 15.
Chem Sci. 2021.
PMID: 35024121
Free PMC article.
Exquisitely Specific anti-KRAS Biodegraders Inform on the Cellular Prevalence of Nucleotide-Loaded States.
Lim S, Khoo R, Juang YC, Gopal P, Zhang H, Yeo C, Peh KM, Teo J, Ng S, Henry B, Partridge AW.
Lim S, et al. Among authors: peh km.
ACS Cent Sci. 2021 Feb 24;7(2):274-291. doi: 10.1021/acscentsci.0c01337. Epub 2020 Dec 28.
ACS Cent Sci. 2021.
PMID: 33655066
Free PMC article.
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bioPROTACs as versatile modulators of intracellular therapeutic targets including proliferating cell nuclear antigen (PCNA).
Lim S, Khoo R, Peh KM, Teo J, Chang SC, Ng S, Beilhartz GL, Melnyk RA, Johannes CW, Brown CJ, Lane DP, Henry B, Partridge AW.
Lim S, et al. Among authors: peh km.
Proc Natl Acad Sci U S A. 2020 Mar 17;117(11):5791-5800. doi: 10.1073/pnas.1920251117. Epub 2020 Mar 2.
Proc Natl Acad Sci U S A. 2020.
PMID: 32123106
Free PMC article.
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