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A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization.
Zampetidis CP, Galanos P, Angelopoulou A, Zhu Y, Polyzou A, Karamitros T, Kotsinas A, Lagopati N, Mourkioti I, Mirzazadeh R, Polyzos A, Garnerone S, Mizi A, Gusmao EG, Sofiadis K, Gál Z, Larsen DH, Pefani DE, Demaria M, Tsirigos A, Crosetto N, Maya-Mendoza A, Papaspyropoulos A, Evangelou K, Bartek J, Papantonis A, Gorgoulis VG. Zampetidis CP, et al. Among authors: pefani de. Mol Cell. 2021 Dec 2;81(23):4907-4923.e8. doi: 10.1016/j.molcel.2021.10.017. Epub 2021 Nov 17. Mol Cell. 2021. PMID: 34793711 Free article.
A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence.
Komseli ES, Pateras IS, Krejsgaard T, Stawiski K, Rizou SV, Polyzos A, Roumelioti FM, Chiourea M, Mourkioti I, Paparouna E, Zampetidis CP, Gumeni S, Trougakos IP, Pefani DE, O'Neill E, Gagos S, Eliopoulos AG, Fendler W, Chowdhury D, Bartek J, Gorgoulis VG. Komseli ES, et al. Among authors: pefani de. BMC Genomics. 2018 Jan 10;19(1):37. doi: 10.1186/s12864-017-4375-1. BMC Genomics. 2018. PMID: 29321003 Free PMC article.
Correction to: A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced senescence.
Komseli ES, Pateras IS, Krejsgaard T, Stawiski K, Rizou SV, Polyzos A, Roumelioti FM, Chiourea M, Mourkioti I, Paparouna E, Zampetidis CP, Gumeni S, Trougakos IP, Pefani DE, O'Neill E, Gagos S, Eliopoulos AG, Fendler W, Chowdhury D, Bartek J, Gorgoulis VG. Komseli ES, et al. Among authors: pefani de. BMC Genomics. 2021 May 5;22(1):327. doi: 10.1186/s12864-021-07608-z. BMC Genomics. 2021. PMID: 33952190 Free PMC article. No abstract available.
53BP1-mediated recruitment of RASSF1A to ribosomal DNA breaks promotes local ATM signaling.
Tsaridou S, Velimezi G, Willenbrock F, Chatzifrangkeskou M, Elsayed W, Panagopoulos A, Karamitros D, Gorgoulis V, Lygerou Z, Roukos V, O'Neill E, Pefani DE. Tsaridou S, et al. Among authors: pefani de. EMBO Rep. 2022 Aug 3;23(8):e54483. doi: 10.15252/embr.202154483. Epub 2022 Jun 27. EMBO Rep. 2022. PMID: 35758159 Free PMC article.
RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73.
Papaspyropoulos A, Bradley L, Thapa A, Leung CY, Toskas K, Koennig D, Pefani DE, Raso C, Grou C, Hamilton G, Vlahov N, Grawenda A, Haider S, Chauhan J, Buti L, Kanapin A, Lu X, Buffa F, Dianov G, von Kriegsheim A, Matallanas D, Samsonova A, Zernicka-Goetz M, O'Neill E. Papaspyropoulos A, et al. Among authors: pefani de. Nat Commun. 2018 Jan 30;9(1):424. doi: 10.1038/s41467-017-02786-5. Nat Commun. 2018. PMID: 29382819 Free PMC article.
Ribosomal DNA and the nucleolus at the heart of aging.
Kasselimi E, Pefani DE, Taraviras S, Lygerou Z. Kasselimi E, et al. Among authors: pefani de. Trends Biochem Sci. 2022 Apr;47(4):328-341. doi: 10.1016/j.tibs.2021.12.007. Epub 2022 Jan 18. Trends Biochem Sci. 2022. PMID: 35063340 Review.
RASSF1A is required for the maintenance of nuclear actin levels.
Chatzifrangkeskou M, Pefani DE, Eyres M, Vendrell I, Fischer R, Pankova D, O'Neill E. Chatzifrangkeskou M, et al. Among authors: pefani de. EMBO J. 2019 Aug 15;38(16):e101168. doi: 10.15252/embj.2018101168. Epub 2019 Jun 7. EMBO J. 2019. PMID: 31414556 Free PMC article.
21 results