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Ultrasensitive Genetically Encoded Indicator for Hydrogen Peroxide Identifies Roles for the Oxidant in Cell Migration and Mitochondrial Function.
Pak VV, Ezeriņa D, Lyublinskaya OG, Pedre B, Tyurin-Kuzmin PA, Mishina NM, Thauvin M, Young D, Wahni K, Martínez Gache SA, Demidovich AD, Ermakova YG, Maslova YD, Shokhina AG, Eroglu E, Bilan DS, Bogeski I, Michel T, Vriz S, Messens J, Belousov VV. Pak VV, et al. Among authors: pedre b. Cell Metab. 2020 Mar 3;31(3):642-653.e6. doi: 10.1016/j.cmet.2020.02.003. Cell Metab. 2020. PMID: 32130885 Free PMC article.
Protein Promiscuity in H2O2 Signaling.
Young D, Pedre B, Ezeriņa D, De Smet B, Lewandowska A, Tossounian MA, Bodra N, Huang J, Astolfi Rosado L, Van Breusegem F, Messens J. Young D, et al. Among authors: pedre b. Antioxid Redox Signal. 2019 Apr 1;30(10):1285-1324. doi: 10.1089/ars.2017.7013. Epub 2018 Jun 6. Antioxid Redox Signal. 2019. PMID: 29635930 Review.
Structural snapshots of OxyR reveal the peroxidatic mechanism of H2O2 sensing.
Pedre B, Young D, Charlier D, Mourenza Á, Rosado LA, Marcos-Pascual L, Wahni K, Martens E, G de la Rubia A, Belousov VV, Mateos LM, Messens J. Pedre B, et al. Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):E11623-E11632. doi: 10.1073/pnas.1807954115. Epub 2018 Nov 21. Proc Natl Acad Sci U S A. 2018. PMID: 30463959 Free PMC article.
The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis.
Rosado LA, Wahni K, Degiacomi G, Pedre B, Young D, de la Rubia AG, Boldrin F, Martens E, Marcos-Pascual L, Sancho-Vaello E, Albesa-Jové D, Provvedi R, Martin C, Makarov V, Versées W, Verniest G, Guerin ME, Mateos LM, Manganelli R, Messens J. Rosado LA, et al. Among authors: pedre b. J Biol Chem. 2017 Aug 11;292(32):13097-13110. doi: 10.1074/jbc.M117.797837. Epub 2017 Jun 15. J Biol Chem. 2017. PMID: 28620052 Free PMC article.
Chemistry and Redox Biology of Mycothiol.
Reyes AM, Pedre B, De Armas MI, Tossounian MA, Radi R, Messens J, Trujillo M. Reyes AM, et al. Among authors: pedre b. Antioxid Redox Signal. 2018 Feb 20;28(6):487-504. doi: 10.1089/ars.2017.7074. Epub 2017 May 10. Antioxid Redox Signal. 2018. PMID: 28372502 Review.
19 results