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Dysregulated splicing factor SF3B1 unveils a dual therapeutic vulnerability to target pancreatic cancer cells and cancer stem cells with an anti-splicing drug.
Alors-Perez E, Blázquez-Encinas R, Alcalá S, Viyuela-García C, Pedraza-Arevalo S, Herrero-Aguayo V, Jiménez-Vacas JM, Mafficini A, Sánchez-Frías ME, Cano MT, Abollo-Jiménez F, Marín-Sanz JA, Cabezas-Sainz P, Lawlor RT, Luchini C, Sánchez L, Sánchez-Hidalgo JM, Ventura S, Martin-Hijano L, Gahete MD, Scarpa A, Arjona-Sánchez Á, Ibáñez-Costa A, Sainz B Jr, Luque RM, Castaño JP. Alors-Perez E, et al. Among authors: pedraza arevalo s. J Exp Clin Cancer Res. 2021 Dec 2;40(1):382. doi: 10.1186/s13046-021-02153-9. J Exp Clin Cancer Res. 2021. PMID: 34857016 Free PMC article.
Ghrelin O-acyltransferase (GOAT) enzyme is overexpressed in prostate cancer, and its levels are associated with patient's metabolic status: Potential value as a non-invasive biomarker.
Hormaechea-Agulla D, Gómez-Gómez E, Ibáñez-Costa A, Carrasco-Valiente J, Rivero-Cortés E, L-López F, Pedraza-Arevalo S, Valero-Rosa J, Sánchez-Sánchez R, Ortega-Salas R, Moreno MM, Gahete MD, López-Miranda J, Requena MJ, Castaño JP, Luque RM. Hormaechea-Agulla D, et al. Cancer Lett. 2016 Dec 1;383(1):125-134. doi: 10.1016/j.canlet.2016.09.022. Epub 2016 Sep 28. Cancer Lett. 2016. PMID: 27693462
Ghrelin-O-Acyltransferase (GOAT) Enzyme as a Novel Potential Biomarker in Gastroenteropancreatic Neuroendocrine Tumors.
Herrera-Martínez AD, Gahete MD, Sánchez-Sánchez R, Alors-Perez E, Pedraza-Arevalo S, Serrano-Blanch R, Martínez-Fuentes AJ, Gálvez-Moreno MA, Castaño JP, Luque RM. Herrera-Martínez AD, et al. Clin Transl Gastroenterol. 2018 Oct 8;9(10):196. doi: 10.1038/s41424-018-0058-8. Clin Transl Gastroenterol. 2018. PMID: 30297816 Free PMC article.
Mouse models in endocrine tumors.
Gahete MD, Jimenez-Vacas JM, Alors-Perez E, Herrero-Aguayo V, Fuentes-Fayos AC, Pedraza-Arevalo S, Castaño JP, Luque RM. Gahete MD, et al. J Endocrinol. 2018 Nov 1:JOE-18-0571.R1. doi: 10.1530/JOE-18-0571. Online ahead of print. J Endocrinol. 2018. PMID: 30475226 Free article. Review.
Oncogenic Role of Secreted Engrailed Homeobox 2 (EN2) in Prostate Cancer.
Gómez-Gómez E, Jiménez-Vacas JM, Pedraza-Arévalo S, López-López F, Herrero-Aguayo V, Hormaechea-Agulla D, Valero-Rosa J, Ibáñez-Costa A, León-González AJ, Sánchez-Sánchez R, González-Serrano T, Requena-Tapia MJ, Castaño JP, Carrasco-Valiente J, Gahete MD, Luque RM. Gómez-Gómez E, et al. J Clin Med. 2019 Sep 6;8(9):1400. doi: 10.3390/jcm8091400. J Clin Med. 2019. PMID: 31500112 Free PMC article.
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