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Guanylin and uroguanylin mRNA expression is increased following Roux-en-Y gastric bypass, but guanylins do not play a significant role in body weight regulation and glycemic control.
Fernandez-Cachon ML, Pedersen SL, Rigbolt KT, Zhang C, Fabricius K, Hansen HH, Elster L, Fink LN, Schäfer M, Rhee NA, Langholz E, Wandall E, Friis SU, Vilmann P, Kristiansen VB, Schmidt C, Schreiter K, Breitschopf K, Hübschle T, Jorsal T, Vilsbøll T, Schmidt T, Theis S, Knop FK, Larsen PJ, Jelsing J. Fernandez-Cachon ML, et al. Among authors: pedersen sl. Peptides. 2018 Mar;101:32-43. doi: 10.1016/j.peptides.2017.12.024. Epub 2017 Dec 28. Peptides. 2018. PMID: 29289697 Clinical Trial.
An Aldehyde Responsive, Cleavable Linker for Glucose Responsive Insulins.
Mannerstedt K, Mishra NK, Engholm E, Lundh M, Madsen CS, Pedersen PJ, Le-Huu P, Pedersen SL, Buch-Månson N, Borgström B, Brimert T, Fink LN, Fosgerau K, Vrang N, Jensen KJ. Mannerstedt K, et al. Among authors: pedersen pj, pedersen sl. Chemistry. 2021 Feb 10;27(9):3166-3176. doi: 10.1002/chem.202004878. Epub 2021 Jan 15. Chemistry. 2021. PMID: 33169429
Neoglycolipids for Prolonging the Effects of Peptides: Self-Assembling Glucagon-like Peptide 1 Analogues with Albumin Binding Properties and Potent in Vivo Efficacy.
van Witteloostuijn SB, Mannerstedt K, Wismann P, Bech EM, Thygesen MB, Vrang N, Jelsing J, Jensen KJ, Pedersen SL. van Witteloostuijn SB, et al. Among authors: pedersen sl. Mol Pharm. 2017 Jan 3;14(1):193-205. doi: 10.1021/acs.molpharmaceut.6b00787. Epub 2016 Dec 22. Mol Pharm. 2017. PMID: 28005376
108 results