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Multifaceted Bioanalytical Methods for the Comprehensive Pharmacokinetic and Catabolic Assessment of MEDI3726, an Anti-Prostate-Specific Membrane Antigen Pyrrolobenzodiazepine Antibody-Drug Conjugate.
Huang Y, Del Nagro CJ, Balic K, Mylott WR Jr, Ismaiel OA, Ma E, Faria M, Wheeler AM, Yuan M, Waldron MP, Peay MG, Cortes DF, Roskos L, Liang M, Rosenbaum AI. Huang Y, et al. Among authors: peay mg. Anal Chem. 2020 Aug 18;92(16):11135-11144. doi: 10.1021/acs.analchem.0c01187. Epub 2020 Jul 1. Anal Chem. 2020. PMID: 32459957 Free article. Clinical Trial.
Development and validation of a hybrid immunoaffinity LC-MS/MS assay for quantitation of total antibody (TAb) from an antibody drug conjugate (ADC) PYX-201 in human plasma.
Yin F, Adhikari D, Peay M, Cortes D, Garada M, Shane Woolf M, Ma E, Lebarbenchon D, Mylott W, Dyszel M, Harriman S, Pinkas J. Yin F, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2023 Aug 1;1228:123844. doi: 10.1016/j.jchromb.2023.123844. Epub 2023 Jul 26. J Chromatogr B Analyt Technol Biomed Life Sci. 2023. PMID: 37579604