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Page 1
Phosphoinositide acyl chain saturation drives CD8+ effector T cell signaling and function.
Edwards-Hicks J, Apostolova P, Buescher JM, Maib H, Stanczak MA, Corrado M, Klein Geltink RI, Maccari ME, Villa M, Carrizo GE, Sanin DE, Baixauli F, Kelly B, Curtis JD, Haessler F, Patterson A, Field CS, Caputa G, Kyle RL, Soballa M, Cha M, Paul H, Martin J, Grzes KM, Flachsmann L, Mitterer M, Zhao L, Winkler F, Rafei-Shamsabadi DA, Meiss F, Bengsch B, Zeiser R, Puleston DJ, O'Sullivan D, Pearce EJ, Pearce EL. Edwards-Hicks J, et al. Among authors: pearce ej. Nat Immunol. 2023 Mar;24(3):516-530. doi: 10.1038/s41590-023-01419-y. Epub 2023 Feb 2. Nat Immunol. 2023. PMID: 36732424 Free PMC article.
Prostaglandin E 2 controls the metabolic adaptation of T cells to the intestinal microenvironment.
Villa M, Sanin DE, Apostolova P, Corrado M, Kabat AM, Cristinzio C, Regina A, Carrizo GE, Rana N, Stanczak MA, Baixauli F, Grzes KM, Cupovic J, Solagna F, Hackl A, Globig AM, Hässler F, Puleston DJ, Kelly B, Cabezas-Wallscheid N, Hasselblatt P, Bengsch B, Zeiser R, Sagar, Buescher JM, Pearce EJ, Pearce EL. Villa M, et al. Among authors: pearce ej. bioRxiv [Preprint]. 2023 Mar 15:2023.03.13.532431. doi: 10.1101/2023.03.13.532431. bioRxiv. 2023. PMID: 36993703 Free PMC article. Updated. Preprint.
Metabolism in type 2 immune responses.
Kabat AM, Pearce EL, Pearce EJ. Kabat AM, et al. Among authors: pearce ej. Immunity. 2023 Apr 11;56(4):723-741. doi: 10.1016/j.immuni.2023.03.007. Immunity. 2023. PMID: 37044062 Free PMC article. Review.
Metabolic and functional remodeling of colonic macrophages in response to high-fat diet-induced obesity.
Castoldi A, Sanin DE, van Teijlingen Bakker N, Aguiar CF, de Brito Monteiro L, Rana N, Grzes KM, Kabat AM, Curtis J, Cameron AM, Caputa G, Antônio de Souza T, Souto FO, Buescher JM, Edwards-Hicks J, Pearce EL, Pearce EJ, Saraiva Camara NO. Castoldi A, et al. Among authors: pearce ej. iScience. 2023 Aug 25;26(10):107719. doi: 10.1016/j.isci.2023.107719. eCollection 2023 Oct 20. iScience. 2023. PMID: 37674984 Free PMC article.
Prostaglandin E2 controls the metabolic adaptation of T cells to the intestinal microenvironment.
Villa M, Sanin DE, Apostolova P, Corrado M, Kabat AM, Cristinzio C, Regina A, Carrizo GE, Rana N, Stanczak MA, Baixauli F, Grzes KM, Cupovic J, Solagna F, Hackl A, Globig AM, Hässler F, Puleston DJ, Kelly B, Cabezas-Wallscheid N, Hasselblatt P, Bengsch B, Zeiser R, Sagar, Buescher JM, Pearce EJ, Pearce EL. Villa M, et al. Among authors: pearce ej. Nat Commun. 2024 Jan 11;15(1):451. doi: 10.1038/s41467-024-44689-2. Nat Commun. 2024. PMID: 38200005 Free PMC article.
Helminth egg derivatives as proregenerative immunotherapies.
Maestas DR Jr, Chung L, Han J, Wang X, Sommerfeld SD, Kelly SH, Moore E, Nguyen HH, Mejías JC, Peña AN, Zhang H, Hooks JST, Chin AF, Andorko JI, Berlinicke CA, Krishnan K, Choi Y, Anderson AE, Mahatme R, Mejia C, Eric M, Woo J, Ganguly S, Zack DJ, Zhao L, Pearce EJ, Housseau F, Pardoll DM, Elisseeff JH. Maestas DR Jr, et al. Among authors: pearce ej. Proc Natl Acad Sci U S A. 2023 Feb 21;120(8):e2211703120. doi: 10.1073/pnas.2211703120. Epub 2023 Feb 13. Proc Natl Acad Sci U S A. 2023. PMID: 36780522 Free PMC article.
Metabolic reprogramming of tumor-associated macrophages using glutamine antagonist JHU083 drives tumor immunity in myeloid-rich prostate and bladder cancer tumors.
Praharaj M, Shen F, Lee AJ, Zhao L, Nirschl TR, Theodros D, Singh AK, Wang X, Adusei KM, Lombardo KA, Williams RA, Sena LA, Thompson EA, Tam A, Yegnasubramanian S, Pearce EJ, Leone RD, Alt J, Rais R, Slusher BS, Pardoll DM, Powell JD, Zarif JC. Praharaj M, et al. Among authors: pearce ej. Cancer Immunol Res. 2024 May 3. doi: 10.1158/2326-6066.CIR-23-1105. Online ahead of print. Cancer Immunol Res. 2024. PMID: 38701369
Metabolic rewiring tunes dermal macrophages in staphylococcal skin infection.
Forde AJ, Kolter J, Zwicky P, Baasch S, Lohrmann F, Eckert M, Gres V, Lagies S, Gorka O, Rambold AS, Buescher JM, Kammerer B, Lachmann N, Prinz M, Groß O, Pearce EJ, Becher B, Henneke P. Forde AJ, et al. Among authors: pearce ej. Sci Immunol. 2023 Aug 18;8(86):eadg3517. doi: 10.1126/sciimmunol.adg3517. Epub 2023 Aug 11. Sci Immunol. 2023. PMID: 37566679
Resident TH2 cells orchestrate adipose tissue remodeling at a site adjacent to infection.
Kabat AM, Hackl A, Sanin DE, Zeis P, Grzes KM, Baixauli F, Kyle R, Caputa G, Edwards-Hicks J, Villa M, Rana N, Curtis JD, Castoldi A, Cupovic J, Dreesen L, Sibilia M, Pospisilik JA, Urban JF Jr, Grün D, Pearce EL, Pearce EJ. Kabat AM, et al. Among authors: pearce ej. Sci Immunol. 2022 Oct 21;7(76):eadd3263. doi: 10.1126/sciimmunol.add3263. Epub 2022 Oct 14. Sci Immunol. 2022. PMID: 36240286
234 results