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Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability.
Nelson DM, Jaber-Hijazi F, Cole JJ, Robertson NA, Pawlikowski JS, Norris KT, Criscione SW, Pchelintsev NA, Piscitello D, Stong N, Rai TS, McBryan T, Otte GL, Nixon C, Clark W, Riethman H, Wu H, Schotta G, Garcia BA, Neretti N, Baird DM, Berger SL, Adams PD. Nelson DM, et al. Among authors: pchelintsev na. Genome Biol. 2016 Jul 25;17(1):158. doi: 10.1186/s13059-016-1017-x. Genome Biol. 2016. PMID: 27457071 Free PMC article.
HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia.
Rai TS, Cole JJ, Nelson DM, Dikovskaya D, Faller WJ, Vizioli MG, Hewitt RN, Anannya O, McBryan T, Manoharan I, van Tuyn J, Morrice N, Pchelintsev NA, Ivanov A, Brock C, Drotar ME, Nixon C, Clark W, Sansom OJ, Anderson KI, King A, Blyth K, Adams PD. Rai TS, et al. Among authors: pchelintsev na. Genes Dev. 2014 Dec 15;28(24):2712-25. doi: 10.1101/gad.247528.114. Genes Dev. 2014. PMID: 25512559 Free PMC article.
Age-associated increase in heterochromatic marks in murine and primate tissues.
Kreiling JA, Tamamori-Adachi M, Sexton AN, Jeyapalan JC, Munoz-Najar U, Peterson AL, Manivannan J, Rogers ES, Pchelintsev NA, Adams PD, Sedivy JM. Kreiling JA, et al. Among authors: pchelintsev na. Aging Cell. 2011 Apr;10(2):292-304. doi: 10.1111/j.1474-9726.2010.00666.x. Epub 2010 Dec 30. Aging Cell. 2011. PMID: 21176091 Free PMC article.
Profiling of transcriptional and epigenetic changes during directed endothelial differentiation of human embryonic stem cells identifies FOXA2 as a marker of early mesoderm commitment.
Howard L, Mackenzie RM, Pchelintsev NA, McBryan T, McClure JD, McBride MW, Kane NM, Adams PD, Milligan G, Baker AH. Howard L, et al. Among authors: pchelintsev na. Stem Cell Res Ther. 2013 Apr 24;4(2):36. doi: 10.1186/scrt192. Stem Cell Res Ther. 2013. PMID: 23618383 Free PMC article.
15 results