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Scaffold Hybridization Strategy Leads to the Discovery of Dopamine D3 Receptor-Selective or Multitarget Bitopic Ligands Potentially Useful for Central Nervous System Disorders.
Bonifazi A, Newman AH, Keck TM, Gervasoni S, Vistoli G, Del Bello F, Giorgioni G, Pavletić P, Quaglia W, Piergentili A. Bonifazi A, et al. Among authors: pavletic p. ACS Chem Neurosci. 2021 Oct 6;12(19):3638-3649. doi: 10.1021/acschemneuro.1c00368. Epub 2021 Sep 16. ACS Chem Neurosci. 2021. PMID: 34529404 Free PMC article.
Highly Potent and Selective Dopamine D4 Receptor Antagonists Potentially Useful for the Treatment of Glioblastoma.
Pavletić P, Semeano A, Yano H, Bonifazi A, Giorgioni G, Piergentili A, Quaglia W, Sabbieti MG, Agas D, Santoni G, Pallini R, Ricci-Vitiani L, Sabato E, Vistoli G, Del Bello F. Pavletić P, et al. J Med Chem. 2022 Sep 22;65(18):12124-12139. doi: 10.1021/acs.jmedchem.2c00840. Epub 2022 Sep 13. J Med Chem. 2022. PMID: 36098685 Free PMC article.
Novel Highly Potent and Selective Sigma1 Receptor Antagonists Effectively Block the Binge Eating Episode in Female Rats.
Cifani C, Micioni Di Bonaventura E, Botticelli L, Del Bello F, Giorgioni G, Pavletić P, Piergentili A, Quaglia W, Bonifazi A, Schepmann D, Wünsch B, Vistoli G, Micioni Di Bonaventura MV. Cifani C, et al. Among authors: pavletic p. ACS Chem Neurosci. 2020 Oct 7;11(19):3107-3116. doi: 10.1021/acschemneuro.0c00456. Epub 2020 Sep 21. ACS Chem Neurosci. 2020. PMID: 32886484 Free PMC article.