The radiosensitising effect of gemcitabine and its main metabolite dFdU under low oxygen conditions is in vitro not dependent on functional HIF-1 protein.
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BMC Cancer. 2014 Aug 16;14:594. doi: 10.1186/1471-2407-14-594.
BMC Cancer. 2014.
PMID: 25128202
Free PMC article.