Paung Y - Search Results

1

Mutation in Abl kinase with altered drug-binding kinetics indicates a novel mechanism of imatinib resistance.

Lyczek A, Berger BT, Rangwala AM, Paung Y, Tom J, Philipose H, Guo J, Albanese SK, Robers MB, Knapp S, Chodera JD, Seeliger MA. Lyczek A, et al. Among authors: paung y. Proc Natl Acad Sci U S A. 2021 Nov 16;118(46):e2111451118. doi: 10.1073/pnas.2111451118. Proc Natl Acad Sci U S A. 2021. PMID: 34750265 Free PMC article.

2

KA1 Domains: Unity in Mechanistic Diversity.

Paung Y, Seeliger MA. Paung Y, et al. Structure. 2018 Aug 7;26(8):1045-1047. doi: 10.1016/j.str.2018.07.002. Structure. 2018. PMID: 30089246 Free article.

3

Prolyl isomerization of FAAP20 catalyzed by PIN1 regulates the Fanconi anemia pathway.

Wang J, Chan B, Tong M, Paung Y, Jo U, Martin D, Seeliger M, Haley J, Kim H. Wang J, et al. Among authors: paung y. PLoS Genet. 2019 Feb 21;15(2):e1007983. doi: 10.1371/journal.pgen.1007983. eCollection 2019 Feb. PLoS Genet. 2019. PMID: 30789902 Free PMC article.

4

Validation of an Allosteric Binding Site of Src Kinase Identified by Unbiased Ligand Binding Simulations.

Mingione VR, Foda ZH, Paung Y, Philipose H, Rangwala AM, Shan Y, Seeliger MA. Mingione VR, et al. Among authors: paung y. J Mol Biol. 2022 Sep 15;434(17):167628. doi: 10.1016/j.jmb.2022.167628. Epub 2022 May 17. J Mol Biol. 2022. PMID: 35595169 Free PMC article.

5

Extended DNA-binding interfaces beyond the canonical SAP domain contribute to the function of replication stress regulator SDE2 at DNA replication forks.

Weinheimer AS, Paung Y, Rageul J, Khan A, Lo N, Ho B, Tong M, Alphonse S, Seeliger MA, Kim H. Weinheimer AS, et al. Among authors: paung y. J Biol Chem. 2022 Aug;298(8):102268. doi: 10.1016/j.jbc.2022.102268. Epub 2022 Jul 16. J Biol Chem. 2022. PMID: 35850305 Free PMC article.

6

IFITM proteins assist cellular uptake of diverse linked chemotypes.

Lou K, Wassarman DR, Yang T, Paung Y, Zhang Z, O'Loughlin TA, Moore MK, Egan RK, Greninger P, Benes CH, Seeliger MA, Taunton J, Gilbert LA, Shokat KM. Lou K, et al. Among authors: paung y. Science. 2022 Dec 9;378(6624):1097-1104. doi: 10.1126/science.abl5829. Epub 2022 Dec 8. Science. 2022. PMID: 36480603 Free PMC article.

7

Allosteric regulation and inhibition of protein kinases.

Mingione VR, Paung Y, Outhwaite IR, Seeliger MA. Mingione VR, et al. Among authors: paung y. Biochem Soc Trans. 2023 Feb 27;51(1):373-385. doi: 10.1042/BST20220940. Biochem Soc Trans. 2023. PMID: 36794774 Free PMC article. Review.

8

Biochemical Studies of Systemic Lupus Erythematosus-Associated Mutations in Nonreceptor Tyrosine Kinases Ack1 and Brk.

Kan Y, Paung Y, Kim Y, Seeliger MA, Miller WT. Kan Y, et al. Among authors: paung y. Biochemistry. 2023 Mar 21;62(6):1124-1137. doi: 10.1021/acs.biochem.2c00685. Epub 2023 Feb 28. Biochemistry. 2023. PMID: 36854171 Free PMC article.

9

Domain Architecture of the Nonreceptor Tyrosine Kinase Ack1.

Kan Y, Paung Y, Seeliger MA, Miller WT. Kan Y, et al. Among authors: paung y. Cells. 2023 Mar 15;12(6):900. doi: 10.3390/cells12060900. Cells. 2023. PMID: 36980241 Free PMC article. Review.

10

Structural mechanism of a drug-binding process involving a large conformational change of the protein target.

Ayaz P, Lyczek A, Paung Y, Mingione VR, Iacob RE, de Waal PW, Engen JR, Seeliger MA, Shan Y, Shaw DE. Ayaz P, et al. Among authors: paung y. Nat Commun. 2023 Apr 5;14(1):1885. doi: 10.1038/s41467-023-36956-5. Nat Commun. 2023. PMID: 37019905 Free PMC article.

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