Pauly T - Search Results

1

Biophysical and pharmacokinetic characterization of a small-molecule inhibitor of RUNX1/ETO tetramerization with anti-leukemic effects.

Gopalswamy M, Kroeger T, Bickel D, Frieg B, Akter S, Schott-Verdugo S, Viegas A, Pauly T, Mayer M, Przibilla J, Reiners J, Nagel-Steger L, Smits SHJ, Groth G, Etzkorn M, Gohlke H. Gopalswamy M, et al. Among authors: pauly t. Sci Rep. 2022 Aug 19;12(1):14158. doi: 10.1038/s41598-022-17913-6. Sci Rep. 2022. PMID: 35986043 Free PMC article.

2

Met/Val129 polymorphism of the full-length human prion protein dictates distinct pathways of amyloid formation.

Pauly T, Bolakhrif N, Kaiser J, Nagel-Steger L, Gremer L, Gohlke H, Willbold D. Pauly T, et al. J Biol Chem. 2022 Oct;298(10):102430. doi: 10.1016/j.jbc.2022.102430. Epub 2022 Aug 28. J Biol Chem. 2022. PMID: 36037966 Free PMC article.

3

Stoichiometric Zn²⁺ interferes with the self-association of Aβ42: Insights from size distribution analysis.

Zhang T, Pauly T, Nagel-Steger L. Zhang T, et al. Among authors: pauly t. Int J Biol Macromol. 2018 Jul 1;113:631-639. doi: 10.1016/j.ijbiomac.2018.02.123. Epub 2018 Feb 22. Int J Biol Macromol. 2018. PMID: 29476859

4

Versatile Route toward Hydrophobically Polymer-Grafted Gold Nanoparticles from Aqueous Dispersions.

Sindram J, Krüsmann M, Otten M, Pauly T, Nagel-Steger L, Karg M. Sindram J, et al. Among authors: pauly t. J Phys Chem B. 2021 Jul 29;125(29):8225-8237. doi: 10.1021/acs.jpcb.1c03772. Epub 2021 Jul 14. J Phys Chem B. 2021. PMID: 34260239

5

Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis.

Pandit J, Danley DE, Schulte GK, Mazzalupo S, Pauly TA, Hayward CM, Hamanaka ES, Thompson JF, Harwood HJ Jr. Pandit J, et al. Among authors: pauly ta. J Biol Chem. 2000 Sep 29;275(39):30610-7. doi: 10.1074/jbc.M004132200. J Biol Chem. 2000. PMID: 10896663 Free article.

6

Structure-activity analysis of the purine binding site of human liver glycogen phosphorylase.

Ekstrom JL, Pauly TA, Carty MD, Soeller WC, Culp J, Danley DE, Hoover DJ, Treadway JL, Gibbs EM, Fletterick RJ, Day YS, Myszka DG, Rath VL. Ekstrom JL, et al. Chem Biol. 2002 Aug;9(8):915-24. doi: 10.1016/s1074-5521(02)00186-2. Chem Biol. 2002. PMID: 12204691

7

Inhibition of MMP-1 and MMP-13 with phosphinic acids that exploit binding in the S2 pocket.

Reiter LA, Rizzi JP, Pandit J, Lasut MJ, McGahee SM, Parikh VD, Blake JF, Danley DE, Laird ER, Lopez-Anaya A, Lopresti-Morrow LL, Mansour MN, Martinelli GJ, Mitchell PG, Owens BS, Pauly TA, Reeves LM, Schulte GK, Yocum SA. Reiter LA, et al. Among authors: pauly ta. Bioorg Med Chem Lett. 1999 Jan 18;9(2):127-32. doi: 10.1016/s0960-894x(98)00729-x. Bioorg Med Chem Lett. 1999. PMID: 10021913

8

A crystallizable form of RIIbeta regulatory domain obtained by limited proteolysis.

Danley DE, Haggan ME, Cunningham D, Fennell KF, Pauly TA, LeMotte PK. Danley DE, et al. Among authors: pauly ta. Acta Crystallogr D Biol Crystallogr. 2000 Aug;56(Pt 8):1038-41. doi: 10.1107/s0907444900007150. Acta Crystallogr D Biol Crystallogr. 2000. PMID: 10944347

9

Specificity determinants of human cathepsin s revealed by crystal structures of complexes.

Pauly TA, Sulea T, Ammirati M, Sivaraman J, Danley DE, Griffor MC, Kamath AV, Wang IK, Laird ER, Seddon AP, Ménard R, Cygler M, Rath VL. Pauly TA, et al. Biochemistry. 2003 Mar 25;42(11):3203-13. doi: 10.1021/bi027308i. Biochemistry. 2003. PMID: 12641451

10

X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase.

Pauly TA, Ekstrom JL, Beebe DA, Chrunyk B, Cunningham D, Griffor M, Kamath A, Lee SE, Madura R, Mcguire D, Subashi T, Wasilko D, Watts P, Mylari BL, Oates PJ, Adams PD, Rath VL. Pauly TA, et al. Structure. 2003 Sep;11(9):1071-85. doi: 10.1016/s0969-2126(03)00167-9. Structure. 2003. PMID: 12962626 Free article.

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