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B cells imprint adoptively transferred CD8+ T cells with enhanced tumor immunity.
Smith AS, Knochelmann HM, Wyatt MM, Rangel Rivera GO, Rivera-Reyes AM, Dwyer CJ, Ware MB, Cole AC, Neskey DM, Rubinstein MP, Liu B, Thaxton JE, Bartee E, Paulos CM. Smith AS, et al. Among authors: paulos cm. J Immunother Cancer. 2022 Jan;10(1):e003078. doi: 10.1136/jitc-2021-003078. J Immunother Cancer. 2022. PMID: 35017148 Free PMC article.
T-cell receptor gene therapy of established tumors in a murine melanoma model.
Abad JD, Wrzensinski C, Overwijk W, De Witte MA, Jorritsma A, Hsu C, Gattinoni L, Cohen CJ, Paulos CM, Palmer DC, Haanen JB, Schumacher TN, Rosenberg SA, Restifo NP, Morgan RA. Abad JD, et al. Among authors: paulos cm. J Immunother. 2008 Jan;31(1):1-6. doi: 10.1097/CJI.0b013e31815c193f. J Immunother. 2008. PMID: 18157006 Free PMC article.
Type 17 CD8+ T cells display enhanced antitumor immunity.
Hinrichs CS, Kaiser A, Paulos CM, Cassard L, Sanchez-Perez L, Heemskerk B, Wrzesinski C, Borman ZA, Muranski P, Restifo NP. Hinrichs CS, et al. Among authors: paulos cm. Blood. 2009 Jul 16;114(3):596-9. doi: 10.1182/blood-2009-02-203935. Epub 2009 May 26. Blood. 2009. PMID: 19471017 Free PMC article.
Ex vivo interleukin-12-priming during CD8(+) T cell activation dramatically improves adoptive T cell transfer antitumor efficacy in a lymphodepleted host.
Rubinstein MP, Cloud CA, Garrett TE, Moore CJ, Schwartz KM, Johnson CB, Craig DH, Salem ML, Paulos CM, Cole DJ. Rubinstein MP, et al. Among authors: paulos cm. J Am Coll Surg. 2012 Apr;214(4):700-7; discussion 707-8. doi: 10.1016/j.jamcollsurg.2011.12.034. Epub 2012 Feb 22. J Am Coll Surg. 2012. PMID: 22360982 Free PMC article.
The inducible costimulator augments Tc17 cell responses to self and tumor tissue.
Nelson MH, Kundimi S, Bowers JS, Rogers CE, Huff LW, Schwartz KM, Thyagarajan K, Little EC, Mehrotra S, Cole DJ, Rubinstein MP, Paulos CM. Nelson MH, et al. Among authors: paulos cm. J Immunol. 2015 Feb 15;194(4):1737-47. doi: 10.4049/jimmunol.1401082. Epub 2015 Jan 9. J Immunol. 2015. PMID: 25576595 Free PMC article.
Interleukin-12 enhances the function and anti-tumor activity in murine and human CD8(+) T cells.
Rubinstein MP, Su EW, Suriano S, Cloud CA, Andrijauskaite K, Kesarwani P, Schwartz KM, Williams KM, Johnson CB, Li M, Scurti GM, Salem ML, Paulos CM, Garrett-Mayer E, Mehrotra S, Cole DJ. Rubinstein MP, et al. Among authors: paulos cm. Cancer Immunol Immunother. 2015 May;64(5):539-49. doi: 10.1007/s00262-015-1655-y. Epub 2015 Feb 13. Cancer Immunol Immunother. 2015. PMID: 25676709 Free PMC article.
112 results