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Patient iPSC models reveal glia-intrinsic phenotypes in multiple sclerosis.
Clayton BLL, Barbar L, Sapar M, Rusielewicz T, Kalpana K, Migliori B; NYSCF Global Stem Cell Array® Team; Paull D, Brenner K, Moroziewicz D, Sand IK, Casaccia P, Tesar PJ, Fossati V. Clayton BLL, et al. Among authors: paull d. bioRxiv [Preprint]. 2023 Aug 2:2023.08.01.551553. doi: 10.1101/2023.08.01.551553. bioRxiv. 2023. PMID: 37577713 Free PMC article. Preprint.
Altered transcriptome and disease-related phenotype emerge only after fibroblasts harvested from patients with age-related macular degeneration are differentiated into retinal pigment epithelium.
Cai H, Gong J; NYSCF Global Stem Cell Array Team; Noggle S, Paull D, Rizzolo LJ, Del Priore LV, Fields MA. Cai H, et al. Among authors: paull d. Exp Eye Res. 2021 Jun;207:108576. doi: 10.1016/j.exer.2021.108576. Epub 2021 Apr 22. Exp Eye Res. 2021. PMID: 33895162 Free article.
Integrating deep learning and unbiased automated high-content screening to identify complex disease signatures in human fibroblasts.
Schiff L, Migliori B, Chen Y, Carter D, Bonilla C, Hall J, Fan M, Tam E, Ahadi S, Fischbacher B, Geraschenko A, Hunter CJ, Venugopalan S, DesMarteau S, Narayanaswamy A, Jacob S, Armstrong Z, Ferrarotto P, Williams B, Buckley-Herd G, Hazard J, Goldberg J, Coram M, Otto R, Baltz EA, Andres-Martin L, Pritchard O, Duren-Lubanski A, Daigavane A, Reggio K; NYSCF Global Stem Cell Array® Team; Nelson PC, Frumkin M, Solomon SL, Bauer L, Aiyar RS, Schwarzbach E, Noggle SA, Monsma FJ Jr, Paull D, Berndl M, Yang SJ, Johannesson B. Schiff L, et al. Among authors: paull d. Nat Commun. 2022 Mar 25;13(1):1590. doi: 10.1038/s41467-022-28423-4. Nat Commun. 2022. PMID: 35338121 Free PMC article.
A dual SHOX2:GFP; MYH6:mCherry knockin hESC reporter line for derivation of human SAN-like cells.
Ghazizadeh Z, Zhu J, Fattahi F, Tang A, Sun X, Amin S, Tsai SY, Khalaj M, Zhou T, Samuel RM, Zhang T, Ortega FA, Gordillo M, Moroziewicz D; NYSCF Global Stem Cell Array® Team; Paull D, Noggle SA, Xiang JZ, Studer L, Christini DJ, Pitt GS, Evans T, Chen S. Ghazizadeh Z, et al. Among authors: paull d. iScience. 2022 Mar 25;25(4):104153. doi: 10.1016/j.isci.2022.104153. eCollection 2022 Apr 15. iScience. 2022. PMID: 35434558 Free PMC article.
Reactive Astrocytes Derived From Human Induced Pluripotent Stem Cells Suppress Oligodendrocyte Precursor Cell Differentiation.
Smith MD, Chamling X, Gill AJ, Martinez H, Li W, Fitzgerald KC, Sotirchos ES, Moroziewicz D, Bauer L, Paull D, Gharagozloo M, Bhargava P, Zack DJ, Fossati V, Calabresi PA. Smith MD, et al. Among authors: paull d. Front Mol Neurosci. 2022 May 6;15:874299. doi: 10.3389/fnmol.2022.874299. eCollection 2022. Front Mol Neurosci. 2022. PMID: 35600072 Free PMC article.
A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants.
Han Y, Tan L, Zhou T, Yang L, Carrau L, Lacko LA, Saeed M, Zhu J, Zhao Z, Nilsson-Payant BE, Lira Neto FT, Cahir C, Giani AM, Chai JC, Li Y, Dong X, Moroziewicz D; NYSCF Global Stem Cell Array Team; Paull D, Zhang T, Koo S, Tan C, Danziger R, Ba Q, Feng L, Chen Z, Zhong A, Wise GJ, Xiang JZ, Wang H, Schwartz RE, tenOever BR, Noggle SA, Rice CM, Qi Q, Evans T, Chen S. Han Y, et al. Among authors: paull d. Cell Stem Cell. 2022 Oct 6;29(10):1475-1490.e6. doi: 10.1016/j.stem.2022.09.008. Cell Stem Cell. 2022. PMID: 36206731 Free PMC article.
184 results