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RyR2 C-terminal truncating variants identified in patients with arrhythmic phenotypes exert a dominant negative effect through formation of wildtype-truncation heteromers.
Biochem J. 2023 Sep 13;480(17):1379-1395. doi: 10.1042/BCJ20230254.
Biochem J. 2023.
PMID: 37492947
RyR2 Serine-2030 PKA Site Governs Ca2+ Release Termination and Ca2+ Alternans.
Wei J, Guo W, Wang R, Paul Estillore J, Belke D, Chen YX, Vallmitjana A, Benitez R, Hove-Madsen L, Chen SRW.
Wei J, et al. Among authors: paul estillore j.
Circ Res. 2023 Jan 20;132(2):e59-e77. doi: 10.1161/CIRCRESAHA.122.321177. Epub 2022 Dec 30.
Circ Res. 2023.
PMID: 36583384
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Ca2+-CaM Dependent Inactivation of RyR2 Underlies Ca2+ Alternans in Intact Heart.
Wei J, Yao J, Belke D, Guo W, Zhong X, Sun B, Wang R, Paul Estillore J, Vallmitjana A, Benitez R, Hove-Madsen L, Alvarez-Lacalle E, Echebarria B, Chen SRW.
Wei J, et al. Among authors: paul estillore j.
Circ Res. 2021 Feb 19;128(4):e63-e83. doi: 10.1161/CIRCRESAHA.120.318429. Epub 2020 Dec 30.
Circ Res. 2021.
PMID: 33375811
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