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Tanycytes control hypothalamic liraglutide uptake and its anti-obesity actions.
Imbernon M, Saponaro C, Helms HCC, Duquenne M, Fernandois D, Deligia E, Denis RGP, Chao DHM, Rasika S, Staels B, Pattou F, Pfrieger FW, Brodin B, Luquet S, Bonner C, Prevot V. Imbernon M, et al. Among authors: pattou f. Cell Metab. 2022 Jul 5;34(7):1054-1063.e7. doi: 10.1016/j.cmet.2022.06.002. Epub 2022 Jun 17. Cell Metab. 2022. PMID: 35716660 Free PMC article.
Proteasomal degradation of retinoid X receptor alpha reprograms transcriptional activity of PPARgamma in obese mice and humans.
Lefebvre B, Benomar Y, Guédin A, Langlois A, Hennuyer N, Dumont J, Bouchaert E, Dacquet C, Pénicaud L, Casteilla L, Pattou F, Ktorza A, Staels B, Lefebvre P. Lefebvre B, et al. Among authors: pattou f. J Clin Invest. 2010 May;120(5):1454-68. doi: 10.1172/JCI38606. Epub 2010 Apr 1. J Clin Invest. 2010. PMID: 20364085 Free PMC article.
PPARβ/δ activation induces enteroendocrine L cell GLP-1 production.
Daoudi M, Hennuyer N, Borland MG, Touche V, Duhem C, Gross B, Caiazzo R, Kerr-Conte J, Pattou F, Peters JM, Staels B, Lestavel S. Daoudi M, et al. Among authors: pattou f. Gastroenterology. 2011 May;140(5):1564-74. doi: 10.1053/j.gastro.2011.01.045. Epub 2011 Feb 4. Gastroenterology. 2011. PMID: 21300064 Free article.
The nuclear orphan receptor Nur77 is a lipotoxicity sensor regulating glucose-induced insulin secretion in pancreatic β-cells.
Briand O, Helleboid-Chapman A, Ploton M, Hennuyer N, Carpentier R, Pattou F, Vandewalle B, Moerman E, Gmyr V, Kerr-Conte J, Eeckhoute J, Staels B, Lefebvre P. Briand O, et al. Among authors: pattou f. Mol Endocrinol. 2012 Mar;26(3):399-413. doi: 10.1210/me.2011-1317. Epub 2012 Feb 2. Mol Endocrinol. 2012. PMID: 22301783 Free PMC article.
Human adipose tissue macrophages display activation of cancer-related pathways.
Mayi TH, Daoudi M, Derudas B, Gross B, Bories G, Wouters K, Brozek J, Caiazzo R, Raverdi V, Pigeyre M, Allavena P, Mantovani A, Pattou F, Staels B, Chinetti-Gbaguidi G. Mayi TH, et al. Among authors: pattou f. J Biol Chem. 2012 Jun 22;287(26):21904-13. doi: 10.1074/jbc.M111.315200. Epub 2012 Apr 17. J Biol Chem. 2012. PMID: 22511784 Free PMC article.
515 results