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Exercise training decreases the concentration of malonyl-CoA and increases the expression and activity of malonyl-CoA decarboxylase in human muscle.
Kuhl JE, Ruderman NB, Musi N, Goodyear LJ, Patti ME, Crunkhorn S, Dronamraju D, Thorell A, Nygren J, Ljungkvist O, Degerblad M, Stahle A, Brismar TB, Andersen KL, Saha AK, Efendic S, Bavenholm PN. Kuhl JE, et al. Among authors: patti me. Am J Physiol Endocrinol Metab. 2006 Jun;290(6):E1296-303. doi: 10.1152/ajpendo.00341.2005. Epub 2006 Jan 24. Am J Physiol Endocrinol Metab. 2006. PMID: 16434556 Free article. Clinical Trial.
Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation.
Crunkhorn S, Dearie F, Mantzoros C, Gami H, da Silva WS, Espinoza D, Faucette R, Barry K, Bianco AC, Patti ME. Crunkhorn S, et al. Among authors: patti me. J Biol Chem. 2007 May 25;282(21):15439-50. doi: 10.1074/jbc.M611214200. Epub 2007 Apr 6. J Biol Chem. 2007. PMID: 17416903 Free article.
Expression of the splicing factor gene SFRS10 is reduced in human obesity and contributes to enhanced lipogenesis.
Pihlajamäki J, Lerin C, Itkonen P, Boes T, Floss T, Schroeder J, Dearie F, Crunkhorn S, Burak F, Jimenez-Chillaron JC, Kuulasmaa T, Miettinen P, Park PJ, Nasser I, Zhao Z, Zhang Z, Xu Y, Wurst W, Ren H, Morris AJ, Stamm S, Goldfine AB, Laakso M, Patti ME. Pihlajamäki J, et al. Among authors: patti me. Cell Metab. 2011 Aug 3;14(2):208-18. doi: 10.1016/j.cmet.2011.06.007. Cell Metab. 2011. PMID: 21803291 Free PMC article.
Metabolic Effects of Long-Term Reduction in Free Fatty Acids With Acipimox in Obesity: A Randomized Trial.
Makimura H, Stanley TL, Suresh C, De Sousa-Coelho AL, Frontera WR, Syu S, Braun LR, Looby SE, Feldpausch MN, Torriani M, Lee H, Patti ME, Grinspoon SK. Makimura H, et al. Among authors: patti me. J Clin Endocrinol Metab. 2016 Mar;101(3):1123-33. doi: 10.1210/jc.2015-3696. Epub 2015 Dec 21. J Clin Endocrinol Metab. 2016. PMID: 26691888 Free PMC article. Clinical Trial.
Dietary Betaine Supplementation Increases Fgf21 Levels to Improve Glucose Homeostasis and Reduce Hepatic Lipid Accumulation in Mice.
Ejaz A, Martinez-Guino L, Goldfine AB, Ribas-Aulinas F, De Nigris V, Ribó S, Gonzalez-Franquesa A, Garcia-Roves PM, Li E, Dreyfuss JM, Gall W, Kim JK, Bottiglieri T, Villarroya F, Gerszten RE, Patti ME, Lerin C. Ejaz A, et al. Among authors: patti me. Diabetes. 2016 Apr;65(4):902-12. doi: 10.2337/db15-1094. Epub 2016 Feb 8. Diabetes. 2016. PMID: 26858359 Free PMC article.
Defects in muscle branched-chain amino acid oxidation contribute to impaired lipid metabolism.
Lerin C, Goldfine AB, Boes T, Liu M, Kasif S, Dreyfuss JM, De Sousa-Coelho AL, Daher G, Manoli I, Sysol JR, Isganaitis E, Jessen N, Goodyear LJ, Beebe K, Gall W, Venditti CP, Patti ME. Lerin C, et al. Among authors: patti me. Mol Metab. 2016 Aug 6;5(10):926-936. doi: 10.1016/j.molmet.2016.08.001. eCollection 2016 Oct. Mol Metab. 2016. PMID: 27689005 Free PMC article.
176 results