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Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction.
Janbandhu V, Tallapragada V, Patrick R, Li Y, Abeygunawardena D, Humphreys DT, Martin EMMA, Ward AO, Contreras O, Farbehi N, Yao E, Du J, Dunwoodie SL, Bursac N, Harvey RP. Janbandhu V, et al. Among authors: patrick r. Cell Stem Cell. 2022 Feb 3;29(2):281-297.e12. doi: 10.1016/j.stem.2021.10.009. Epub 2021 Nov 10. Cell Stem Cell. 2022. PMID: 34762860 Free PMC article.
Transcriptional heterogeneity of fibroblasts is a hallmark of the aging heart.
Vidal R, Wagner JUG, Braeuning C, Fischer C, Patrick R, Tombor L, Muhly-Reinholz M, John D, Kliem M, Conrad T, Guimarães-Camboa N, Harvey R, Dimmeler S, Sauer S. Vidal R, et al. Among authors: patrick r. JCI Insight. 2019 Nov 14;4(22):e131092. doi: 10.1172/jci.insight.131092. JCI Insight. 2019. PMID: 31723062 Free PMC article.
Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction.
Tombor LS, John D, Glaser SF, Luxán G, Forte E, Furtado M, Rosenthal N, Baumgarten N, Schulz MH, Wittig J, Rogg EM, Manavski Y, Fischer A, Muhly-Reinholz M, Klee K, Looso M, Selignow C, Acker T, Bibli SI, Fleming I, Patrick R, Harvey RP, Abplanalp WT, Dimmeler S. Tombor LS, et al. Among authors: patrick r. Nat Commun. 2021 Jan 29;12(1):681. doi: 10.1038/s41467-021-20905-1. Nat Commun. 2021. PMID: 33514719 Free PMC article.
Quantitative trait and transcriptome analysis of genetic complexity underpinning cardiac interatrial septation in mice using an advanced intercross line.
Moradi Marjaneh M, Kirk EP, Patrick R, Alankarage D, Humphreys DT, Del Monte-Nieto G, Cornejo-Paramo P, Janbandhu V, Doan TB, Dunwoodie SL, Wong ES, Moran C, Martin ICA, Thomson PC, Harvey RP. Moradi Marjaneh M, et al. Among authors: patrick r. Elife. 2023 Jun 5;12:e83606. doi: 10.7554/eLife.83606. Elife. 2023. PMID: 37272612 Free PMC article.
Fibulin-3 is necessary to prevent cardiac rupture following myocardial infarction.
Murtha LA, Hardy SA, Mabotuwana NS, Bigland MJ, Bailey T, Raguram K, Liu S, Ngo DT, Sverdlov AL, Tomin T, Birner-Gruenberger R, Hume RD, Iismaa SE, Humphreys DT, Patrick R, Chong JJH, Lee RJ, Harvey RP, Graham RM, Rainer PP, Boyle AJ. Murtha LA, et al. Among authors: patrick r. Sci Rep. 2023 Sep 11;13(1):14995. doi: 10.1038/s41598-023-41894-9. Sci Rep. 2023. PMID: 37696945 Free PMC article.
417 results