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Year Number of Results
2014 2
2015 4
2016 13
2017 7
2018 5
2019 8
2020 10
2021 3
2022 1
2024 0

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45 results

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Page 1
Assessment of inhalation toxicity of cigarette smoke and aerosols from flavor mixtures: 5-week study in A/J mice.
Wong ET, Luettich K, Cammack L, Chua CS, Sciuscio D, Merg C, Corciulo M, Piault R, Ashutosh K, Smith C, Leroy P, Moine F, Glabasnia A, Diana P, Chia C, Tung CK, Ivanov N, Hoeng J, Peitsch M, Lee KM, Vanscheeuwijck P. Wong ET, et al. Among authors: leroy p. J Appl Toxicol. 2022 Oct;42(10):1701-1722. doi: 10.1002/jat.4338. Epub 2022 Jun 8. J Appl Toxicol. 2022. PMID: 35543240 Free PMC article.
A 6-month inhalation toxicology study in Apoe-/- mice demonstrates substantially lower effects of e-vapor aerosol compared with cigarette smoke in the respiratory tract.
Wong ET, Szostak J, Titz B, Lee T, Wong SK, Lavrynenko O, Merg C, Corciulo M, Simicevic J, Auberson M, Peric D, Dulize R, Bornand D, Loh GJ, Lee KM, Zhang J, Miller JH 4th, Schlage WK, Guedj E, Schneider T, Phillips B, Leroy P, Choukrallah MA, Sierro N, Buettner A, Xiang Y, Kuczaj A, Ivanov NV, Luettich K, Vanscheeuwijck P, Peitsch MC, Hoeng J. Wong ET, et al. Among authors: leroy p. Arch Toxicol. 2021 May;95(5):1805-1829. doi: 10.1007/s00204-021-03020-4. Epub 2021 May 7. Arch Toxicol. 2021. PMID: 33963423 Free PMC article.
Impact of whole-body versus nose-only inhalation exposure systems on systemic, respiratory, and cardiovascular endpoints in a 2-month cigarette smoke exposure study in the ApoE-/- mouse model.
Kogel U, Wong ET, Szostak J, Tan WT, Lucci F, Leroy P, Titz B, Xiang Y, Low T, Wong SK, Guedj E, Ivanov NV, Schlage WK, Peitsch MC, Kuczaj A, Vanscheeuwijck P, Hoeng J. Kogel U, et al. Among authors: leroy p. J Appl Toxicol. 2021 Oct;41(10):1598-1619. doi: 10.1002/jat.4149. Epub 2021 Apr 6. J Appl Toxicol. 2021. PMID: 33825214 Free PMC article.
Comparison of the biological impact of aerosol of e-vapor device with MESH® technology and cigarette smoke on human bronchial and alveolar cultures.
Giralt A, Iskandar AR, Martin F, Moschini E, Serchi T, Kondylis A, Marescotti D, Leroy P, Ortega-Torres L, Majeed S, Merg C, Trivedi K, Guedj E, Frentzel S, Ivanov NV, Peitsch MC, Gutleb AC, Hoeng J. Giralt A, et al. Among authors: leroy p. Toxicol Lett. 2021 Feb 1;337:98-110. doi: 10.1016/j.toxlet.2020.11.006. Epub 2020 Nov 18. Toxicol Lett. 2021. PMID: 33220401 Free article.
Comparing the preclinical risk profile of inhalable candidate and potential candidate modified risk tobacco products: A bridging use case.
Schlage WK, Titz B, Iskandar A, Poussin C, Van der Toorn M, Wong ET, Pratte P, Maeder S, Schaller JP, Pospisil P, Boue S, Vuillaume G, Leroy P, Martin F, Ivanov NV, Peitsch MC, Hoeng J. Schlage WK, et al. Among authors: leroy p. Toxicol Rep. 2020 Sep 12;7:1187-1206. doi: 10.1016/j.toxrep.2020.09.004. eCollection 2020. Toxicol Rep. 2020. PMID: 32995294 Free PMC article.
Respiratory Effects of Exposure to Aerosol From the Candidate Modified-Risk Tobacco Product THS 2.2 in an 18-Month Systems Toxicology Study With A/J Mice.
Titz B, Sewer A, Luettich K, Wong ET, Guedj E, Nury C, Schneider T, Xiang Y, Trivedi K, Vuillaume G, Leroy P, Büttner A, Martin F, Ivanov NV, Vanscheeuwijck P, Hoeng J, Peitsch MC. Titz B, et al. Among authors: leroy p. Toxicol Sci. 2020 Nov 1;178(1):138-158. doi: 10.1093/toxsci/kfaa132. Toxicol Sci. 2020. PMID: 32780831 Free PMC article.
Reduced Chronic Toxicity and Carcinogenicity in A/J Mice in Response to Life-Time Exposure to Aerosol From a Heated Tobacco Product Compared With Cigarette Smoke.
Wong ET, Luettich K, Krishnan S, Wong SK, Lim WT, Yeo D, Büttner A, Leroy P, Vuillaume G, Boué S, Hoeng J, Vanscheeuwijck P, Peitsch MC. Wong ET, et al. Among authors: leroy p. Toxicol Sci. 2020 Nov 1;178(1):44-70. doi: 10.1093/toxsci/kfaa131. Toxicol Sci. 2020. PMID: 32780830 Free PMC article.
Multi-omics systems toxicology study of mouse lung assessing the effects of aerosols from two heat-not-burn tobacco products and cigarette smoke.
Titz B, Szostak J, Sewer A, Phillips B, Nury C, Schneider T, Dijon S, Lavrynenko O, Elamin A, Guedj E, Tsin Wong E, Lebrun S, Vuillaume G, Kondylis A, Gubian S, Cano S, Leroy P, Keppler B, Ivanov NV, Vanscheeuwijck P, Martin F, Peitsch MC, Hoeng J. Titz B, et al. Among authors: leroy p. Comput Struct Biotechnol J. 2020 Apr 25;18:1056-1073. doi: 10.1016/j.csbj.2020.04.011. eCollection 2020. Comput Struct Biotechnol J. 2020. PMID: 32419906 Free PMC article.
E-vapor aerosols do not compromise bone integrity relative to cigarette smoke after 6-month inhalation in an ApoE-/- mouse model.
Reumann MK, Schaefer J, Titz B, Aspera-Werz RH, Wong ET, Szostak J, Häussling V, Ehnert S, Leroy P, Tan WT, Kuczaj A, Audretsch C, Springer F, Badke A, Augat P, Quentanilla-Fend L, Martella M, Lee KM, Peitsch MC, Hoeng J, Nussler AK. Reumann MK, et al. Among authors: leroy p. Arch Toxicol. 2020 Jun;94(6):2163-2177. doi: 10.1007/s00204-020-02769-4. Epub 2020 May 14. Arch Toxicol. 2020. PMID: 32409933 Free PMC article.
Evaluation of toxicity of aerosols from flavored e-liquids in Sprague-Dawley rats in a 90-day OECD inhalation study, complemented by transcriptomics analysis.
Ho J, Sciuscio D, Kogel U, Titz B, Leroy P, Vuillaume G, Talikka M, Martin E, Pospisil P, Lebrun S, Xia W, Lee T, Chng YX, Phillips BW, Veljkovic E, Guedj E, Xiang Y, Ivanov NV, Peitsch MC, Hoeng J, Vanscheeuwijck P. Ho J, et al. Among authors: leroy p. Arch Toxicol. 2020 Jun;94(6):2179-2206. doi: 10.1007/s00204-020-02759-6. Epub 2020 May 5. Arch Toxicol. 2020. PMID: 32367274 Free PMC article.
45 results