Patlewicz G - Search Results

1

Application of Cell Painting for chemical hazard evaluation in support of screening-level chemical assessments.

Nyffeler J, Willis C, Harris FR, Foster MJ, Chambers B, Culbreth M, Brockway RE, Davidson-Fritz S, Dawson D, Shah I, Friedman KP, Chang D, Everett LJ, Wambaugh JF, Patlewicz G, Harrill JA. Nyffeler J, et al. Among authors: patlewicz g. Toxicol Appl Pharmacol. 2023 Jun 1;468:116513. doi: 10.1016/j.taap.2023.116513. Epub 2023 Apr 11. Toxicol Appl Pharmacol. 2023. PMID: 37044265

2

Estimating provisional margins of exposure for data-poor chemicals using high-throughput computational methods.

Nicolas CI, Linakis MW, Minto MS, Mansouri K, Clewell RA, Yoon M, Wambaugh JF, Patlewicz G, McMullen PD, Andersen ME, Clewell Iii HJ. Nicolas CI, et al. Among authors: patlewicz g. Front Pharmacol. 2022 Oct 7;13:980747. doi: 10.3389/fphar.2022.980747. eCollection 2022. Front Pharmacol. 2022. PMID: 36278238 Free PMC article.

3

Development of a CSRML version of the Analog Identification Methodology (AIM) fragments and their evaluation within the Generalised Read-Across (GenRA) approach.

Adams M, Hidle H, Chang D, Richard AM, Williams AJ, Shah I, Patlewicz G. Adams M, et al. Among authors: patlewicz g. Comput Toxicol. 2023 Feb 1;25:10.1016/j.comtox.2022.100256. doi: 10.1016/j.comtox.2022.100256. Comput Toxicol. 2023. PMID: 36733411 Free PMC article.

4

Identifying xenobiotic metabolites with in silico prediction tools and LCMS suspect screening analysis.

Boyce M, Favela KA, Bonzo JA, Chao A, Lizarraga LE, Moody LR, Owens EO, Patlewicz G, Shah I, Sobus JR, Thomas RS, Williams AJ, Yau A, Wambaugh JF. Boyce M, et al. Among authors: patlewicz g. Front Toxicol. 2023 Jan 18;5:1051483. doi: 10.3389/ftox.2023.1051483. eCollection 2023. Front Toxicol. 2023. PMID: 36742129 Free PMC article.

5

Repeat-dose toxicity prediction with Generalized Read-Across (GenRA) using targeted transcriptomic data: A proof-of-concept case study.

Tate T, Wambaugh J, Patlewicz G, Shah I. Tate T, et al. Among authors: patlewicz g. Comput Toxicol. 2021 Aug 1;19:1-12. doi: 10.1016/j.comtox.2021.100171. Comput Toxicol. 2021. PMID: 37309449 Free PMC article.

6

Towards systematic read-across using Generalised Read-Across (GenRA).

Patlewicz G, Shah I. Patlewicz G, et al. Comput Toxicol. 2023 Feb;25:1-15. doi: 10.1016/j.comtox.2022.100258. Comput Toxicol. 2023. PMID: 37693774 Free PMC article.

7

Evaluating structure-based activity in a high-throughput assay for steroid biosynthesis.

Foster MJ, Patlewicz G, Shah I, Haggard DE, Judson RS, Paul Friedman K. Foster MJ, et al. Among authors: patlewicz g. Comput Toxicol. 2022 Nov 1;24:1-23. doi: 10.1016/j.comtox.2022.100245. Comput Toxicol. 2022. PMID: 37841081 Free PMC article.

8

Systematic Approaches for the Encoding of Chemical Groups: A Case Study.

Karamertzanis PG, Patlewicz G, Sannicola M, Paul-Friedman K, Shah I. Karamertzanis PG, et al. Among authors: patlewicz g. Chem Res Toxicol. 2024 Apr 15;37(4):600-619. doi: 10.1021/acs.chemrestox.3c00411. Epub 2024 Mar 18. Chem Res Toxicol. 2024. PMID: 38498310

9

Advancing the science of a read-across framework for evaluation of data-poor chemicals incorporating systematic and new approach methods.

Lizarraga LE, Suter GW, Lambert JC, Patlewicz G, Zhao JQ, Dean JL, Kaiser P. Lizarraga LE, et al. Among authors: patlewicz g. Regul Toxicol Pharmacol. 2023 Jan;137:105293. doi: 10.1016/j.yrtph.2022.105293. Epub 2022 Nov 19. Regul Toxicol Pharmacol. 2023. PMID: 36414101

10

Evaluation of Complex Mixture Toxicity in the Milwaukee Estuary (WI, USA) Using Whole-Mixture and Component-Based Evaluation Methods.

Maloney EM, Villeneuve DL, Jensen KM, Blackwell BR, Kahl MD, Poole ST, Vitense K, Feifarek DJ, Patlewicz G, Dean K, Tilton C, Randolph EC, Cavallin JE, LaLone CA, Blatz D, Schaupp CM, Ankley GT. Maloney EM, et al. Among authors: patlewicz g. Environ Toxicol Chem. 2023 Jun;42(6):1229-1256. doi: 10.1002/etc.5571. Epub 2023 Apr 28. Environ Toxicol Chem. 2023. PMID: 36715369

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