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A Stabilized, Monomeric, Receptor Binding Domain Elicits High-Titer Neutralizing Antibodies Against All SARS-CoV-2 Variants of Concern.
Ahmed S, Khan MS, Gayathri S, Singh R, Kumar S, Patel UR, Malladi SK, Rajmani RS, van Vuren PJ, Riddell S, Goldie S, Girish N, Reddy P, Upadhyaya A, Pandey S, Siddiqui S, Tyagi A, Jha S, Pandey R, Khatun O, Narayan R, Tripathi S, McAuley AJ, Singanallur NB, Vasan SS, Ringe RP, Varadarajan R. Ahmed S, et al. Among authors: patel ur. Front Immunol. 2021 Dec 9;12:765211. doi: 10.3389/fimmu.2021.765211. eCollection 2021. Front Immunol. 2021. PMID: 34956193 Free PMC article.
Immunogenicity and Protective Efficacy of a Highly Thermotolerant, Trimeric SARS-CoV-2 Receptor Binding Domain Derivative.
Malladi SK, Patel UR, Rajmani RS, Singh R, Pandey S, Kumar S, Khaleeq S, van Vuren PJ, Riddell S, Goldie S, Gayathri S, Chakraborty D, Kalita P, Pramanick I, Agarwal N, Reddy P, Girish N, Upadhyaya A, Khan MS, Kanjo K, Bhat M, Mani S, Bhattacharyya S, Siddiqui S, Tyagi A, Jha S, Pandey R, Tripathi S, Dutta S, McAuley AJ, Singanallur NB, Vasan SS, Ringe RP, Varadarajan R. Malladi SK, et al. Among authors: patel ur. ACS Infect Dis. 2021 Aug 13;7(8):2546-2564. doi: 10.1021/acsinfecdis.1c00276. Epub 2021 Jul 14. ACS Infect Dis. 2021. PMID: 34260218 Free PMC article.
Discovery and characterization of the N-phenyl-N'-naphthylurea class of p38 kinase inhibitors.
Cirillo PF, Hickey ER, Moss N, Breitfelder S, Betageri R, Fadra T, Gaenzler F, Gilmore T, Goldberg DR, Kamhi V, Kirrane T, Kroe RR, Madwed J, Moriak M, Netherton M, Pargellis CA, Patel UR, Qian KC, Sharma R, Sun S, Swinamer A, Torcellini C, Takahashi H, Tsang M, Xiong Z. Cirillo PF, et al. Among authors: patel ur. Bioorg Med Chem Lett. 2009 May 1;19(9):2386-91. doi: 10.1016/j.bmcl.2009.03.104. Epub 2009 Mar 26. Bioorg Med Chem Lett. 2009. PMID: 19356929
The discovery of carboline analogs as potent MAPKAP-K2 inhibitors.
Wu JP, Wang J, Abeywardane A, Andersen D, Emmanuel M, Gautschi E, Goldberg DR, Kashem MA, Lukas S, Mao W, Martin L, Morwick T, Moss N, Pargellis C, Patel UR, Patnaude L, Peet GW, Skow D, Snow RJ, Ward Y, Werneburg B, White A. Wu JP, et al. Among authors: patel ur. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4664-9. doi: 10.1016/j.bmcl.2007.05.101. Epub 2007 Jun 7. Bioorg Med Chem Lett. 2007. PMID: 17576063
Nonpeptidic, monocharged, cell permeable ligands for the p56lck SH2 domain.
Proudfoot JR, Betageri R, Cardozo M, Gilmore TA, Glynn S, Hickey ER, Jakes S, Kabcenell A, Kirrane TM, Tibolla AK, Lukas S, Patel UR, Sharma R, Yazdanian M, Moss N, Beaulieu PL, Cameron DR, Ferland JM, Gauthier J, Gillard J, Gorys V, Poirier M, Rancourt J, Wernic D, Llinas-Brunet M. Proudfoot JR, et al. Among authors: patel ur. J Med Chem. 2001 Jul 19;44(15):2421-31. doi: 10.1021/jm000446q. J Med Chem. 2001. PMID: 11448224
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