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Optimized Red-Absorbing Dyes for Imaging and Sensing.
Grimm JB, Tkachuk AN, Patel R, Hennigan ST, Gutu A, Dong P, Gandin V, Osowski AM, Holland KL, Liu ZJ, Brown TA, Lavis LD. Grimm JB, et al. Among authors: patel r. J Am Chem Soc. 2023 Oct 25;145(42):23000-23013. doi: 10.1021/jacs.3c05273. Epub 2023 Oct 16. J Am Chem Soc. 2023. PMID: 37842926 Free PMC article.
A general method to fine-tune fluorophores for live-cell and in vivo imaging.
Grimm JB, Muthusamy AK, Liang Y, Brown TA, Lemon WC, Patel R, Lu R, Macklin JJ, Keller PJ, Ji N, Lavis LD. Grimm JB, et al. Among authors: patel r. Nat Methods. 2017 Oct;14(10):987-994. doi: 10.1038/nmeth.4403. Epub 2017 Sep 4. Nat Methods. 2017. PMID: 28869757 Free PMC article.
A general method to optimize and functionalize red-shifted rhodamine dyes.
Grimm JB, Tkachuk AN, Xie L, Choi H, Mohar B, Falco N, Schaefer K, Patel R, Zheng Q, Liu Z, Lippincott-Schwartz J, Brown TA, Lavis LD. Grimm JB, et al. Among authors: patel r. Nat Methods. 2020 Aug;17(8):815-821. doi: 10.1038/s41592-020-0909-6. Epub 2020 Jul 27. Nat Methods. 2020. PMID: 32719532 Free PMC article.
A General Method to Improve Fluorophores Using Deuterated Auxochromes.
Grimm JB, Xie L, Casler JC, Patel R, Tkachuk AN, Falco N, Choi H, Lippincott-Schwartz J, Brown TA, Glick BS, Liu Z, Lavis LD. Grimm JB, et al. Among authors: patel r. JACS Au. 2021 May 24;1(5):690-696. doi: 10.1021/jacsau.1c00006. Epub 2021 Apr 23. JACS Au. 2021. PMID: 34056637 Free PMC article.
2,7-Diaminobenzopyrylium Dyes Are Live-Cell Mitochondrial Stains.
Banala S, Tkachuk AN, Patel R, Kumar P, Brown TA, Lavis LD. Banala S, et al. Among authors: patel r. ACS Bio Med Chem Au. 2022 Jun 15;2(3):307-312. doi: 10.1021/acsbiomedchemau.1c00068. Epub 2022 Feb 28. ACS Bio Med Chem Au. 2022. PMID: 35726328 Free PMC article.
A general method to improve fluorophores for live-cell and single-molecule microscopy.
Grimm JB, English BP, Chen J, Slaughter JP, Zhang Z, Revyakin A, Patel R, Macklin JJ, Normanno D, Singer RH, Lionnet T, Lavis LD. Grimm JB, et al. Among authors: patel r. Nat Methods. 2015 Mar;12(3):244-50, 3 p following 250. doi: 10.1038/nmeth.3256. Epub 2015 Jan 19. Nat Methods. 2015. PMID: 25599551 Free PMC article.
Bright and photostable chemigenetic indicators for extended in vivo voltage imaging.
Abdelfattah AS, Kawashima T, Singh A, Novak O, Liu H, Shuai Y, Huang YC, Campagnola L, Seeman SC, Yu J, Zheng J, Grimm JB, Patel R, Friedrich J, Mensh BD, Paninski L, Macklin JJ, Murphy GJ, Podgorski K, Lin BJ, Chen TW, Turner GC, Liu Z, Koyama M, Svoboda K, Ahrens MB, Lavis LD, Schreiter ER. Abdelfattah AS, et al. Among authors: patel r. Science. 2019 Aug 16;365(6454):699-704. doi: 10.1126/science.aav6416. Epub 2019 Aug 1. Science. 2019. PMID: 31371562
jYCaMP: an optimized calcium indicator for two-photon imaging at fiber laser wavelengths.
Mohr MA, Bushey D, Aggarwal A, Marvin JS, Kim JJ, Marquez EJ, Liang Y, Patel R, Macklin JJ, Lee CY, Tsang A, Tsegaye G, Ahrens AM, Chen JL, Kim DS, Wong AM, Looger LL, Schreiter ER, Podgorski K. Mohr MA, et al. Among authors: patel r. Nat Methods. 2020 Jul;17(7):694-697. doi: 10.1038/s41592-020-0835-7. Epub 2020 May 25. Nat Methods. 2020. PMID: 32451475 Free PMC article.
Sensitive red protein calcium indicators for imaging neural activity.
Dana H, Mohar B, Sun Y, Narayan S, Gordus A, Hasseman JP, Tsegaye G, Holt GT, Hu A, Walpita D, Patel R, Macklin JJ, Bargmann CI, Ahrens MB, Schreiter ER, Jayaraman V, Looger LL, Svoboda K, Kim DS. Dana H, et al. Among authors: patel r. Elife. 2016 Mar 24;5:e12727. doi: 10.7554/eLife.12727. Elife. 2016. PMID: 27011354 Free PMC article.
Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics.
Akerboom J, Carreras Calderón N, Tian L, Wabnig S, Prigge M, Tolö J, Gordus A, Orger MB, Severi KE, Macklin JJ, Patel R, Pulver SR, Wardill TJ, Fischer E, Schüler C, Chen TW, Sarkisyan KS, Marvin JS, Bargmann CI, Kim DS, Kügler S, Lagnado L, Hegemann P, Gottschalk A, Schreiter ER, Looger LL. Akerboom J, et al. Among authors: patel r. Front Mol Neurosci. 2013 Mar 4;6:2. doi: 10.3389/fnmol.2013.00002. eCollection 2013. Front Mol Neurosci. 2013. PMID: 23459413 Free PMC article.
9,557 results