Patel K - Search Results

1

PR-104 plus sorafenib in patients with advanced hepatocellular carcinoma.

Abou-Alfa GK, Chan SL, Lin CC, Chiorean EG, Holcombe RF, Mulcahy MF, Carter WD, Patel K, Wilson WR, Melink TJ, Gutheil JC, Tsao CJ. Abou-Alfa GK, et al. Among authors: patel k. Cancer Chemother Pharmacol. 2011 Aug;68(2):539-45. doi: 10.1007/s00280-011-1671-3. Epub 2011 May 19. Cancer Chemother Pharmacol. 2011. PMID: 21594722 Clinical Trial.

2

A combined pharmacokinetic model for the hypoxia-targeted prodrug PR-104A in humans, dogs, rats and mice predicts species differences in clearance and toxicity.

Patel K, Choy SS, Hicks KO, Melink TJ, Holford NH, Wilson WR. Patel K, et al. Cancer Chemother Pharmacol. 2011 May;67(5):1145-55. doi: 10.1007/s00280-010-1412-z. Epub 2010 Aug 4. Cancer Chemother Pharmacol. 2011. PMID: 20683596

3

Reductive metabolism of the dinitrobenzamide mustard anticancer prodrug PR-104 in mice.

Gu Y, Guise CP, Patel K, Abbattista MR, Li J, Sun X, Atwell GJ, Boyd M, Patterson AV, Wilson WR. Gu Y, et al. Among authors: patel k. Cancer Chemother Pharmacol. 2011 Mar;67(3):543-55. doi: 10.1007/s00280-010-1354-5. Epub 2010 May 15. Cancer Chemother Pharmacol. 2011. PMID: 20473609

4

Mechanism of action and preclinical antitumor activity of the novel hypoxia-activated DNA cross-linking agent PR-104.

Patterson AV, Ferry DM, Edmunds SJ, Gu Y, Singleton RS, Patel K, Pullen SM, Hicks KO, Syddall SP, Atwell GJ, Yang S, Denny WA, Wilson WR. Patterson AV, et al. Among authors: patel k. Clin Cancer Res. 2007 Jul 1;13(13):3922-32. doi: 10.1158/1078-0432.CCR-07-0478. Clin Cancer Res. 2007. PMID: 17606726

5

Analysis of the hypoxia-activated dinitrobenzamide mustard phosphate pre-prodrug PR-104 and its alcohol metabolite PR-104A in plasma and tissues by liquid chromatography-mass spectrometry.

Patel K, Lewiston D, Gu Y, Hicks KO, Wilson WR. Patel K, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Sep 1;856(1-2):302-11. doi: 10.1016/j.jchromb.2007.06.035. Epub 2007 Jul 6. J Chromatogr B Analyt Technol Biomed Life Sci. 2007. PMID: 17644498

6

Oxygen dependence and extravascular transport of hypoxia-activated prodrugs: comparison of the dinitrobenzamide mustard PR-104A and tirapazamine.

Hicks KO, Myint H, Patterson AV, Pruijn FB, Siim BG, Patel K, Wilson WR. Hicks KO, et al. Among authors: patel k. Int J Radiat Oncol Biol Phys. 2007 Oct 1;69(2):560-71. doi: 10.1016/j.ijrobp.2007.05.049. Int J Radiat Oncol Biol Phys. 2007. PMID: 17869669

7

Bystander Effects of Hypoxia-Activated Prodrugs: Agent-Based Modeling Using Three Dimensional Cell Cultures.

Hong CR, Bogle G, Wang J, Patel K, Pruijn FB, Wilson WR, Hicks KO. Hong CR, et al. Among authors: patel k. Front Pharmacol. 2018 Sep 18;9:1013. doi: 10.3389/fphar.2018.01013. eCollection 2018. Front Pharmacol. 2018. PMID: 30279659 Free PMC article.

8

The Role of Bystander Effects in the Antitumor Activity of the Hypoxia-Activated Prodrug PR-104.

Foehrenbacher A, Patel K, Abbattista MR, Guise CP, Secomb TW, Wilson WR, Hicks KO. Foehrenbacher A, et al. Among authors: patel k. Front Oncol. 2013 Oct 7;3:263. doi: 10.3389/fonc.2013.00263. eCollection 2013. Front Oncol. 2013. PMID: 24109591 Free PMC article.

9

Self-determination in minoritized autistic adolescents and adults.

Girolamo T, Birmingham M, Patel K, Ghali S, Campos I, Greene-Pendelton K, Canale R, Larson C, Sterling A, Shogren KA. Girolamo T, et al. Among authors: patel k. medRxiv [Preprint]. 2024 May 3:2024.05.02.24306799. doi: 10.1101/2024.05.02.24306799. medRxiv. 2024. PMID: 38746405 Free PMC article. Preprint.

10

Pancreatic surgery outcomes: multicentre prospective snapshot study in 67 countries.

PancreasGroup.org Collaborative. PancreasGroup.org Collaborative. Br J Surg. 2024 Jan 3;111(1):znad330. doi: 10.1093/bjs/znad330. Br J Surg. 2024. PMID: 38743040 Free PMC article.

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