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Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD.
Hewitt G, Borel V, Segura-Bayona S, Takaki T, Ruis P, Bellelli R, Lehmann LC, Sommerova L, Vancevska A, Tomas-Loba A, Zhu K, Cooper C, Fugger K, Patel H, Goldstone R, Schneider-Luftman D, Herbert E, Stamp G, Brough R, Pettitt S, Lord CJ, West SC, Ahel I, Ahel D, Chapman JR, Deindl S, Boulton SJ. Hewitt G, et al. Among authors: patel h. Mol Cell. 2021 Feb 18;81(4):767-783.e11. doi: 10.1016/j.molcel.2020.12.006. Epub 2020 Dec 16. Mol Cell. 2021. PMID: 33333017 Free PMC article.
A Role for Chromatin Remodeling in Cohesin Loading onto Chromosomes.
Muñoz S, Minamino M, Casas-Delucchi CS, Patel H, Uhlmann F. Muñoz S, et al. Among authors: patel h. Mol Cell. 2019 May 16;74(4):664-673.e5. doi: 10.1016/j.molcel.2019.02.027. Epub 2019 Mar 25. Mol Cell. 2019. PMID: 30922844 Free PMC article.
RTEL1 Regulates G4/R-Loops to Avert Replication-Transcription Collisions.
Kotsantis P, Segura-Bayona S, Margalef P, Marzec P, Ruis P, Hewitt G, Bellelli R, Patel H, Goldstone R, Poetsch AR, Boulton SJ. Kotsantis P, et al. Among authors: patel h. Cell Rep. 2020 Dec 22;33(12):108546. doi: 10.1016/j.celrep.2020.108546. Cell Rep. 2020. PMID: 33357438 Free PMC article.
Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia.
Loukas I, Simeoni F, Milan M, Inglese P, Patel H, Goldstone R, East P, Strohbuecker S, Mitter R, Talsania B, Tang W, Ratcliffe CDH, Sahai E, Shahrezaei V, Scaffidi P. Loukas I, et al. Among authors: patel h. Cancer Cell. 2023 Jan 9;41(1):70-87.e14. doi: 10.1016/j.ccell.2022.10.002. Epub 2022 Nov 3. Cancer Cell. 2023. PMID: 36332625 Free article.
4,998 results