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Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses.
Jaynes JM, Sable R, Ronzetti M, Bautista W, Knotts Z, Abisoye-Ogunniyan A, Li D, Calvo R, Dashnyam M, Singh A, Guerin T, White J, Ravichandran S, Kumar P, Talsania K, Chen V, Ghebremedhin A, Karanam B, Bin Salam A, Amin R, Odzorig T, Aiken T, Nguyen V, Bian Y, Zarif JC, de Groot AE, Mehta M, Fan L, Hu X, Simeonov A, Pate N, Abu-Asab M, Ferrer M, Southall N, Ock CY, Zhao Y, Lopez H, Kozlov S, de Val N, Yates CC, Baljinnyam B, Marugan J, Rudloff U. Jaynes JM, et al. Among authors: pate n. Sci Transl Med. 2020 Feb 12;12(530):eaax6337. doi: 10.1126/scitranslmed.aax6337. Sci Transl Med. 2020. PMID: 32051227 Free PMC article.
Novel Humanized Mesothelin-Expressing Genetically Engineered Mouse Models Underscore Challenges in Delivery of Complex Therapeutics to Pancreatic Cancers.
Hagerty B, O'Sullivan TN, Zhang X, Collins NK, Custer Lawrence W, Bassel LL, Pate N, Xu J, Guerin TM, Kozlov S, Alewine C. Hagerty B, et al. Among authors: pate n. Mol Cancer Ther. 2021 Oct;20(10):2082-2092. doi: 10.1158/1535-7163.MCT-21-0017. Epub 2021 Jul 26. Mol Cancer Ther. 2021. PMID: 34315768 Free PMC article.
T Cell-Mediated Antitumor Immunity Cooperatively Induced By TGFβR1 Antagonism and Gemcitabine Counteracts Reformation of the Stromal Barrier in Pancreatic Cancer.
Li D, Schaub N, Guerin TM, Bapiro TE, Richards FM, Chen V, Talsania K, Kumar P, Gilbert DJ, Schlomer JJ, Kim SJ, Sorber R, Teper Y, Bautista W, Palena C, Ock CY, Jodrell DI, Pate N, Mehta M, Zhao Y, Kozlov S, Rudloff U. Li D, et al. Among authors: pate n. Mol Cancer Ther. 2021 Oct;20(10):1926-1940. doi: 10.1158/1535-7163.MCT-20-0620. Epub 2021 Aug 10. Mol Cancer Ther. 2021. PMID: 34376576 Free PMC article.
Loss of Brca1 and Trp53 in adult mouse mammary ductal epithelium results in development of hormone receptor-positive or hormone receptor-negative tumors, depending on inactivation of Rb family proteins.
Szabova L, Gordon MB, Lu L, Pate N, Bassel L, Iacovelli AJ, Karim B, Homan PJ, Householder DB, Guerin TM, Burkett S, Day AM, Custer W, Weaver Ohler Z. Szabova L, et al. Among authors: pate n. Breast Cancer Res. 2022 Nov 4;24(1):75. doi: 10.1186/s13058-022-01566-4. Breast Cancer Res. 2022. PMID: 36333737 Free PMC article.
Distinct Biomarker Profiles and TCR Sequence Diversity Characterize the Response to PD-L1 Blockade in a Mouse Melanoma Model.
El Meskini R, Atkinson D, Kulaga A, Abdelmaksoud A, Gumprecht M, Pate N, Hayes S, Oberst M, Kaplan IM, Raber P, Van Dyke T, Sharan SK, Hollingsworth R, Day CP, Merlino G, Weaver Ohler Z. El Meskini R, et al. Among authors: pate n. Mol Cancer Res. 2021 Aug;19(8):1422-1436. doi: 10.1158/1541-7786.MCR-20-0881. Epub 2021 Apr 22. Mol Cancer Res. 2021. PMID: 33888600 Free PMC article.
Naturally Acquired Mouse Kidney Parvovirus Infection Produces a Persistent Interstitial Nephritis in Immunocompetent Laboratory Mice.
Edmondson EF, Hsieh WT, Kramer JA, Breed MW, Roelke-Parker ME, Stephens-Devalle J, Pate NM, Bassel LL, Hollingshead MG, Karim BO, Butcher DO, Warner AC, Nagashima K, Gulani J. Edmondson EF, et al. Among authors: pate nm. Vet Pathol. 2020 Nov;57(6):915-925. doi: 10.1177/0300985820953500. Epub 2020 Oct 5. Vet Pathol. 2020. PMID: 33016243
23 results