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Excessive mechanotransduction in sensory neurons causes joint contractures.
Ma S, Dubin AE, Romero LO, Loud M, Salazar A, Chu S, Klier N, Masri S, Zhang Y, Wang Y, Chesler AT, Wilkinson KA, Vásquez V, Marshall KL, Patapoutian A. Ma S, et al. Among authors: patapoutian a. Science. 2023 Jan 13;379(6628):201-206. doi: 10.1126/science.add3598. Epub 2023 Jan 12. Science. 2023. PMID: 36634173 Free PMC article.
Channels: flies feel your pain.
Macpherson LJ, Patapoutian A. Macpherson LJ, et al. Among authors: patapoutian a. Nat Chem Biol. 2010 Apr;6(4):252-3. doi: 10.1038/nchembio.339. Nat Chem Biol. 2010. PMID: 20300095 No abstract available.
TRPA1 contributes to cold hypersensitivity.
del Camino D, Murphy S, Heiry M, Barrett LB, Earley TJ, Cook CA, Petrus MJ, Zhao M, D'Amours M, Deering N, Brenner GJ, Costigan M, Hayward NJ, Chong JA, Fanger CM, Woolf CJ, Patapoutian A, Moran MM. del Camino D, et al. Among authors: patapoutian a. J Neurosci. 2010 Nov 10;30(45):15165-74. doi: 10.1523/JNEUROSCI.2580-10.2010. J Neurosci. 2010. PMID: 21068322 Free PMC article.
A TRP channel that senses cold stimuli and menthol.
Peier AM, Moqrich A, Hergarden AC, Reeve AJ, Andersson DA, Story GM, Earley TJ, Dragoni I, McIntyre P, Bevan S, Patapoutian A. Peier AM, et al. Among authors: patapoutian a. Cell. 2002 Mar 8;108(5):705-15. doi: 10.1016/s0092-8674(02)00652-9. Cell. 2002. PMID: 11893340 Free article.
The Drosophila ortholog of vertebrate TRPA1 regulates thermotaxis.
Rosenzweig M, Brennan KM, Tayler TD, Phelps PO, Patapoutian A, Garrity PA. Rosenzweig M, et al. Among authors: patapoutian a. Genes Dev. 2005 Feb 15;19(4):419-24. doi: 10.1101/gad.1278205. Epub 2005 Jan 28. Genes Dev. 2005. PMID: 15681611 Free PMC article.
121 results