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The mechanosensitive ion channel PIEZO1 is expressed in tendons and regulates physical performance.
Nakamichi R, Ma S, Nonoyama T, Chiba T, Kurimoto R, Ohzono H, Olmer M, Shukunami C, Fuku N, Wang G, Morrison E, Pitsiladis YP, Ozaki T, D'Lima D, Lotz M, Patapoutian A, Asahara H. Nakamichi R, et al. Among authors: patapoutian a. Sci Transl Med. 2022 Jun;14(647):eabj5557. doi: 10.1126/scitranslmed.abj5557. Epub 2022 Jun 1. Sci Transl Med. 2022. PMID: 35648809
Piezo1, a mechanically activated ion channel, is required for vascular development in mice.
Ranade SS, Qiu Z, Woo SH, Hur SS, Murthy SE, Cahalan SM, Xu J, Mathur J, Bandell M, Coste B, Li YS, Chien S, Patapoutian A. Ranade SS, et al. Among authors: patapoutian a. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10347-52. doi: 10.1073/pnas.1409233111. Epub 2014 Jun 23. Proc Natl Acad Sci U S A. 2014. PMID: 24958852 Free PMC article.
Chemical activation of the mechanotransduction channel Piezo1.
Syeda R, Xu J, Dubin AE, Coste B, Mathur J, Huynh T, Matzen J, Lao J, Tully DC, Engels IH, Petrassi HM, Schumacher AM, Montal M, Bandell M, Patapoutian A. Syeda R, et al. Among authors: patapoutian a. Elife. 2015 May 22;4:e07369. doi: 10.7554/eLife.07369. Elife. 2015. PMID: 26001275 Free PMC article.
Structure of the mechanically activated ion channel Piezo1.
Saotome K, Murthy SE, Kefauver JM, Whitwam T, Patapoutian A, Ward AB. Saotome K, et al. Among authors: patapoutian a. Nature. 2018 Feb 22;554(7693):481-486. doi: 10.1038/nature25453. Epub 2017 Dec 20. Nature. 2018. PMID: 29261642 Free PMC article.
Common PIEZO1 Allele in African Populations Causes RBC Dehydration and Attenuates Plasmodium Infection.
Ma S, Cahalan S, LaMonte G, Grubaugh ND, Zeng W, Murthy SE, Paytas E, Gamini R, Lukacs V, Whitwam T, Loud M, Lohia R, Berry L, Khan SM, Janse CJ, Bandell M, Schmedt C, Wengelnik K, Su AI, Honore E, Winzeler EA, Andersen KG, Patapoutian A. Ma S, et al. Among authors: patapoutian a. Cell. 2018 Apr 5;173(2):443-455.e12. doi: 10.1016/j.cell.2018.02.047. Epub 2018 Mar 22. Cell. 2018. PMID: 29576450 Free PMC article.
Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation.
Nonomura K, Lukacs V, Sweet DT, Goddard LM, Kanie A, Whitwam T, Ranade SS, Fujimori T, Kahn ML, Patapoutian A. Nonomura K, et al. Among authors: patapoutian a. Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):12817-12822. doi: 10.1073/pnas.1817070115. Epub 2018 Nov 27. Proc Natl Acad Sci U S A. 2018. PMID: 30482854 Free PMC article.
A role of PIEZO1 in iron metabolism in mice and humans.
Ma S, Dubin AE, Zhang Y, Mousavi SAR, Wang Y, Coombs AM, Loud M, Andolfo I, Patapoutian A. Ma S, et al. Among authors: patapoutian a. Cell. 2021 Feb 18;184(4):969-982.e13. doi: 10.1016/j.cell.2021.01.024. Epub 2021 Feb 10. Cell. 2021. PMID: 33571427 Free PMC article.
121 results