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Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice.
De Logu F, Nassini R, Materazzi S, Carvalho Gonçalves M, Nosi D, Rossi Degl'Innocenti D, Marone IM, Ferreira J, Li Puma S, Benemei S, Trevisan G, Souza Monteiro de Araújo D, Patacchini R, Bunnett NW, Geppetti P. De Logu F, et al. Among authors: patacchini r. Nat Commun. 2017 Dec 1;8(1):1887. doi: 10.1038/s41467-017-01739-2. Nat Commun. 2017. PMID: 29192190 Free PMC article.
The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives.
Nassini R, Fusi C, Materazzi S, Coppi E, Tuccinardi T, Marone IM, De Logu F, Preti D, Tonello R, Chiarugi A, Patacchini R, Geppetti P, Benemei S. Nassini R, et al. Among authors: patacchini r. Br J Pharmacol. 2015 Jul;172(13):3397-411. doi: 10.1111/bph.13129. Epub 2015 Apr 24. Br J Pharmacol. 2015. PMID: 25765567 Free PMC article.
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1.
Trevisani M, Siemens J, Materazzi S, Bautista DM, Nassini R, Campi B, Imamachi N, Andrè E, Patacchini R, Cottrell GS, Gatti R, Basbaum AI, Bunnett NW, Julius D, Geppetti P. Trevisani M, et al. Among authors: patacchini r. Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13519-24. doi: 10.1073/pnas.0705923104. Epub 2007 Aug 7. Proc Natl Acad Sci U S A. 2007. PMID: 17684094 Free PMC article.
Cough: The Emerging Role of the TRPA1 Channel.
Geppetti P, Patacchini R, Nassini R, Materazzi S. Geppetti P, et al. Among authors: patacchini r. Lung. 2010 Jan;188 Suppl 1:S63-8. doi: 10.1007/s00408-009-9201-3. Epub 2009 Nov 30. Lung. 2010. PMID: 20091046 Review.
Transient receptor potential ankyrin 1 channel localized to non-neuronal airway cells promotes non-neurogenic inflammation.
Nassini R, Pedretti P, Moretto N, Fusi C, Carnini C, Facchinetti F, Viscomi AR, Pisano AR, Stokesberry S, Brunmark C, Svitacheva N, McGarvey L, Patacchini R, Damholt AB, Geppetti P, Materazzi S. Nassini R, et al. Among authors: patacchini r. PLoS One. 2012;7(8):e42454. doi: 10.1371/journal.pone.0042454. Epub 2012 Aug 14. PLoS One. 2012. PMID: 22905134 Free PMC article.
202 results