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STING-activating nanoparticles normalize the vascular-immune interface to potentiate cancer immunotherapy.
Wang-Bishop L, Kimmel BR, Ngwa VM, Madden MZ, Baljon JJ, Florian DC, Hanna A, Pastora LE, Sheehy TL, Kwiatkowski AJ, Wehbe M, Wen X, Becker KW, Garland KM, Schulman JA, Shae D, Edwards D, Wolf MM, Delapp R, Christov PP, Beckermann KE, Balko JM, Rathmell WK, Rathmell JC, Chen J, Wilson JT. Wang-Bishop L, et al. Among authors: pastora le. Sci Immunol. 2023 May 12;8(83):eadd1153. doi: 10.1126/sciimmunol.add1153. Epub 2023 May 5. Sci Immunol. 2023. PMID: 37146128 Free PMC article.
Covalent Polymer-RNA Conjugates for Potent Activation of the RIG-I Pathway.
Palmer CR, Pastora LE, Kimmel BR, Pagendarm HM, Kwiatkowski AJ, Stone PT, Arora K, Francini N, Fedorova O, Pyle AM, Wilson JT. Palmer CR, et al. Among authors: pastora le. Adv Healthc Mater. 2024 Apr 22:e2303815. doi: 10.1002/adhm.202303815. Online ahead of print. Adv Healthc Mater. 2024. PMID: 38648653
Nanoparticle Retinoic Acid-Inducible Gene I Agonist for Cancer Immunotherapy.
Wang-Bishop L, Wehbe M, Pastora LE, Yang J, Kimmel BR, Garland KM, Becker KW, Carson CS, Roth EW, Gibson-Corley KN, Ulkoski D, Krishnamurthy V, Fedorova O, Richmond A, Pyle AM, Wilson JT. Wang-Bishop L, et al. Among authors: pastora le. ACS Nano. 2024 May 7;18(18):11631-11643. doi: 10.1021/acsnano.3c06225. Epub 2024 Apr 23. ACS Nano. 2024. PMID: 38652829 Free PMC article.