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Non-nucleoside reverse transcriptase inhibitor-based combination antiretroviral therapy is associated with lower cell-associated HIV RNA and DNA levels compared to protease inhibitor-based therapy.
Pasternak AO, Vroom J, Kootstra NA, Wit FW, de Bruin M, De Francesco D, Bakker M, Sabin CA, Winston A, Prins JM, Reiss P, Berkhout B; Co-morBidity in Relation to Aids (COBRA) Collaboration. Pasternak AO, et al. Elife. 2021 Aug 13;10:e68174. doi: 10.7554/eLife.68174. Elife. 2021. PMID: 34387543 Free PMC article.
The HIV-1 Tat Protein Enhances Splicing at the Major Splice Donor Site.
Mueller N, Pasternak AO, Klaver B, Cornelissen M, Berkhout B, Das AT. Mueller N, et al. Among authors: pasternak ao. J Virol. 2018 Jun 29;92(14):e01855-17. doi: 10.1128/JVI.01855-17. Print 2018 Jul 15. J Virol. 2018. PMID: 29743356 Free PMC article.
Dendritic cells potently purge latent HIV-1 beyond TCR-stimulation, activating the PI3K-Akt-mTOR pathway.
van Montfort T, van der Sluis R, Darcis G, Beaty D, Groen K, Pasternak AO, Pollakis G, Vink M, Westerhout EM, Hamdi M, Bakker M, van der Putten B, Jurriaans S, Prins JH, Jeeninga R, Thomas AAM, Speijer D, Berkhout B. van Montfort T, et al. Among authors: pasternak ao. EBioMedicine. 2019 Apr;42:97-108. doi: 10.1016/j.ebiom.2019.02.014. Epub 2019 Feb 26. EBioMedicine. 2019. PMID: 30824386 Free PMC article.
102 results